NDUFB2 (NADH:ubiquinone oxidoreductase subunit B2)

2016-10-01  

Identity

HGNC
LOCATION
7q34
LOCUSID
ALIAS
AGGG,CI-AGGG
FUSION GENES

Other Information

Locus ID:

NCBI: 4708
MIM: 603838
HGNC: 7697
Ensembl: ENSG00000090266

Variants:

dbSNP: 4708
ClinVar: 4708
TCGA: ENSG00000090266
COSMIC: NDUFB2

RNA/Proteins

Gene IDTranscript IDUniprot
ENSG00000090266ENST00000247866O95178
ENSG00000090266ENST00000247866A4D1T5
ENSG00000090266ENST00000460088C9IZZ2
ENSG00000090266ENST00000461457C9JRV4
ENSG00000090266ENST00000464566H7C5B8
ENSG00000090266ENST00000465506O95178
ENSG00000090266ENST00000465506A4D1T5
ENSG00000090266ENST00000471136C9JXM4
ENSG00000090266ENST00000472695C9IZZ2
ENSG00000090266ENST00000475276C9IZW8
ENSG00000090266ENST00000476181F8WCJ6
ENSG00000090266ENST00000476279O95178
ENSG00000090266ENST00000476279A4D1T5
ENSG00000090266ENST00000476470C9IZZ2
ENSG00000090266ENST00000482954C9IZZ2

Expression (GTEx)

0
10
20
30
40
50
60
70
80
90

Pathways

PathwaySourceExternal ID
Oxidative phosphorylationKEGGko00190
Alzheimer's diseaseKEGGko05010
Huntington's diseaseKEGGko05016
Oxidative phosphorylationKEGGhsa00190
Alzheimer's diseaseKEGGhsa05010
Parkinson's diseaseKEGGhsa05012
Huntington's diseaseKEGGhsa05016
Metabolic pathwaysKEGGhsa01100
NADH dehydrogenase (ubiquinone) 1 beta subcomplexKEGGhsa_M00147
Non-alcoholic fatty liver disease (NAFLD)KEGGhsa04932
Non-alcoholic fatty liver disease (NAFLD)KEGGko04932
NADH dehydrogenase (ubiquinone) 1 beta subcomplexKEGGM00147
MetabolismREACTOMER-HSA-1430728
The citric acid (TCA) cycle and respiratory electron transportREACTOMER-HSA-1428517
Respiratory electron transport, ATP synthesis by chemiosmotic coupling, and heat production by uncoupling proteins.REACTOMER-HSA-163200
Respiratory electron transportREACTOMER-HSA-611105
Complex I biogenesisREACTOMER-HSA-6799198

Protein levels (Protein atlas)

Not detected
Low
Medium
High

References

Pubmed IDYearTitleCitations
381812342024Association of abnormal NDUFB2 and UQCRH expression with venous thromboembolism in patients with liver cirrhosis.0
381812342024Association of abnormal NDUFB2 and UQCRH expression with venous thromboembolism in patients with liver cirrhosis.0
208776242010Genetic variants in nuclear-encoded mitochondrial genes influence AIDS progression.20
208776242010Genetic variants in nuclear-encoded mitochondrial genes influence AIDS progression.20
190645712008Polymorphisms in mitochondrial genes and prostate cancer risk.22
190645712008Polymorphisms in mitochondrial genes and prostate cancer risk.22
147184452004Differential-display polymerase chain reaction identifies nicotinamide adenine dinucleotide-ubiquinone oxidoreductase as an ischemia/reperfusion-regulated gene in cardiomyocytes.3
147184452004Differential-display polymerase chain reaction identifies nicotinamide adenine dinucleotide-ubiquinone oxidoreductase as an ischemia/reperfusion-regulated gene in cardiomyocytes.3

Citation

Dessen P

NDUFB2 (NADH:ubiquinone oxidoreductase subunit B2)

Atlas Genet Cytogenet Oncol Haematol. 2016-10-01

Online version: http://atlasgeneticsoncology.org/gene/56329/ndufb2-(nadh-ubiquinone-oxidoreductase-subunit-b2)