Identity
HGNC
LOCATION
1p36.22
LOCUSID
ALIAS
FBG1,FBX2,Fbs1,NFB42,OCP1
FUSION GENES
Non-annotated gene. Preliminary data : if you are an author who wish to write a full paper/card on this gene, contribute in submission tool
Other Information
Locus ID:
NCBI: 26232
MIM: 607112
HGNC: 13581
Ensembl: ENSG00000116661
Variants:
dbSNP: 26232
ClinVar: 26232
TCGA: ENSG00000116661
COSMIC: FBXO2
RNA/Proteins
| Gene ID | Transcript ID | Uniprot |
|---|---|---|
| ENSG00000116661 | ENST00000354287 | Q9UK22 |
| ENSG00000116661 | ENST00000465901 | R4GNH2 |
| ENSG00000116661 | ENST00000642025 | A0A286YF37 |
Expression (GTEx)
Pathways
Protein levels (Protein atlas)
References
| Pubmed ID | Year | Title | Citations |
|---|---|---|---|
| 37576703 | 2023 | F-box only protein 2 exacerbates non-alcoholic fatty liver disease by targeting the hydroxyl CoA dehydrogenase alpha subunit. | 1 |
| 37576703 | 2023 | F-box only protein 2 exacerbates non-alcoholic fatty liver disease by targeting the hydroxyl CoA dehydrogenase alpha subunit. | 1 |
| 35525855 | 2022 | FBXO2 targets glycosylated SUN2 for ubiquitination and degradation to promote ovarian cancer development. | 12 |
| 35525855 | 2022 | FBXO2 targets glycosylated SUN2 for ubiquitination and degradation to promote ovarian cancer development. | 12 |
| 32931479 | 2020 | Fbxo2 mediates clearance of damaged lysosomes and modifies neurodegeneration in the Niemann-Pick C brain. | 16 |
| 32931479 | 2020 | Fbxo2 mediates clearance of damaged lysosomes and modifies neurodegeneration in the Niemann-Pick C brain. | 16 |
| 29269301 | 2018 | FBXO2, a novel marker for metastasis in human gastric cancer. | 18 |
| 29269301 | 2018 | FBXO2, a novel marker for metastasis in human gastric cancer. | 18 |
| 28341977 | 2017 | Genetic Analysis of FBXO2, FBXO6, FBXO12, and FBXO41 Variants in Han Chinese Patients with Sporadic Parkinson's Disease. | 10 |
| 28534482 | 2017 | An engineered high affinity Fbs1 carbohydrate binding protein for selective capture of N-glycans and N-glycopeptides. | 12 |
| 28341977 | 2017 | Genetic Analysis of FBXO2, FBXO6, FBXO12, and FBXO41 Variants in Han Chinese Patients with Sporadic Parkinson's Disease. | 10 |
| 28534482 | 2017 | An engineered high affinity Fbs1 carbohydrate binding protein for selective capture of N-glycans and N-glycopeptides. | 12 |
| 27487926 | 2016 | Structural analysis of a function-associated loop mutant of the substrate-recognition domain of Fbs1 ubiquitin ligase. | 5 |
| 27756846 | 2016 | SYVN1, NEDD8, and FBXO2 Proteins Regulate ΔF508 Cystic Fibrosis Transmembrane Conductance Regulator (CFTR) Ubiquitin-mediated Proteasomal Degradation. | 21 |
| 27487926 | 2016 | Structural analysis of a function-associated loop mutant of the substrate-recognition domain of Fbs1 ubiquitin ligase. | 5 |
Citation
Dessen P
FBXO2 (F-box protein 2)
Atlas Genet Cytogenet Oncol Haematol. 2016-10-01
Online version: http://atlasgeneticsoncology.org/gene/56334/fbxo2-(f-box-protein-2)
