TBC1D5 (TBC1 domain family member 5)

2016-10-01  

Identity

HGNC
LOCATION
3p24.3
LOCUSID
ALIAS
-
FUSION GENES

Other Information

Locus ID:

NCBI: 9779
MIM: 615740
HGNC: 19166
Ensembl: ENSG00000131374

Variants:

dbSNP: 9779
ClinVar: 9779
TCGA: ENSG00000131374
COSMIC: TBC1D5

RNA/Proteins

Gene IDTranscript IDUniprot
ENSG00000131374ENST00000253692Q92609
ENSG00000131374ENST00000253692B9A6K1
ENSG00000131374ENST00000412981F2Z3I5
ENSG00000131374ENST00000414349C9K0P2
ENSG00000131374ENST00000415814C9JDR8
ENSG00000131374ENST00000425944C9JWX0
ENSG00000131374ENST00000428355C9JW04
ENSG00000131374ENST00000429383Q92609
ENSG00000131374ENST00000429383B9A6K1
ENSG00000131374ENST00000429924C9J3F6
ENSG00000131374ENST00000430169F2Z3I5
ENSG00000131374ENST00000433533C9JMP7
ENSG00000131374ENST00000434420C9JNM0
ENSG00000131374ENST00000444471C9JIU4
ENSG00000131374ENST00000445294C9J397
ENSG00000131374ENST00000446818Q92609
ENSG00000131374ENST00000446863C9JED7
ENSG00000131374ENST00000452492F2Z3I5
ENSG00000131374ENST00000507877F2Z3C3

Expression (GTEx)

0
5
10
15
20
25
30

Protein levels (Protein atlas)

Not detected
Low
Medium
High

References

Pubmed IDYearTitleCitations
323036382020The secreted protein kinase CstK from Coxiella burnetii influences vacuole development and interacts with the GTPase-activating host protein TBC1D5.8
325212752020TBC1D5-Catalyzed Cycling of Rab7 Is Required for Retromer-Mediated Human Papillomavirus Trafficking during Virus Entry.20
323036382020The secreted protein kinase CstK from Coxiella burnetii influences vacuole development and interacts with the GTPase-activating host protein TBC1D5.8
325212752020TBC1D5-Catalyzed Cycling of Rab7 Is Required for Retromer-Mediated Human Papillomavirus Trafficking during Virus Entry.20
291583242018Control of RAB7 activity and localization through the retromer-TBC1D5 complex enables RAB7-dependent mitophagy.106
301115802018TBC1D5 controls the GTPase cycle of Rab7b.24
291583242018Control of RAB7 activity and localization through the retromer-TBC1D5 complex enables RAB7-dependent mitophagy.106
301115802018TBC1D5 controls the GTPase cycle of Rab7b.24
287467152017Identification of Genetic Loci Jointly Influencing Schizophrenia Risk and the Cognitive Traits of Verbal-Numerical Reasoning, Reaction Time, and General Cognitive Function.65
291469122017Structural insights into Legionella RidL-Vps29 retromer subunit interaction reveal displacement of the regulator TBC1D5.29
287467152017Identification of Genetic Loci Jointly Influencing Schizophrenia Risk and the Cognitive Traits of Verbal-Numerical Reasoning, Reaction Time, and General Cognitive Function.65
291469122017Structural insights into Legionella RidL-Vps29 retromer subunit interaction reveal displacement of the regulator TBC1D5.29
278273642016Structural and mechanistic insights into regulation of the retromer coat by TBC1d5.56
278273642016Structural and mechanistic insights into regulation of the retromer coat by TBC1d5.56
246034922014TBC1D5 and the AP2 complex regulate ATG9 trafficking and initiation of autophagy.93

Citation

Dessen P

TBC1D5 (TBC1 domain family member 5)

Atlas Genet Cytogenet Oncol Haematol. 2016-10-01

Online version: http://atlasgeneticsoncology.org/gene/56345/tbc1d5-(tbc1-domain-family-member-5)