Non-annotated gene. Preliminary data : if you are an author who wish to write a full paper/card on this gene, contribute in submission tool
Other Information
Locus ID:
NCBI: 2158
MIM: 300746
HGNC: 3551
Ensembl: ENSG00000101981
Variants:
dbSNP: 2158
ClinVar: 2158
TCGA: ENSG00000101981
COSMIC: F9
RNA/Proteins
| Gene ID | Transcript ID | Uniprot |
|---|---|---|
| ENSG00000101981 | ENST00000218099 | P00740 |
| ENSG00000101981 | ENST00000394090 | P00740 |
Expression (GTEx)
Pathways
PharmGKB
| Entity ID | Name | Type | Evidence | Association | PK | PD | PMIDs |
|---|---|---|---|---|---|---|---|
| PA28660 | GGCX | Gene | Pathway | associated |
References
| Pubmed ID | Year | Title | Citations |
|---|---|---|---|
| 36696202 | 2023 | Whole F9 gene sequencing identified deep intronic variations in genetically unresolved hemophilia B patients. | 2 |
| 36724452 | 2023 | Factor IXa variants resistant to plasma inhibitors enhance clot formation in vivo. | 1 |
| 36787808 | 2023 | An updated interactive database for 1692 genetic variants in coagulation factor IX provides detailed insights into hemophilia B. | 1 |
| 37210691 | 2023 | Structural and functional exploration of three newly identified coagulation factor IX mutations in Chinese hemophilia B patients. | 0 |
| 37678545 | 2023 | Crippling down factor IX for therapeutic gain. | 0 |
| 36696202 | 2023 | Whole F9 gene sequencing identified deep intronic variations in genetically unresolved hemophilia B patients. | 2 |
| 36724452 | 2023 | Factor IXa variants resistant to plasma inhibitors enhance clot formation in vivo. | 1 |
| 36787808 | 2023 | An updated interactive database for 1692 genetic variants in coagulation factor IX provides detailed insights into hemophilia B. | 1 |
| 37210691 | 2023 | Structural and functional exploration of three newly identified coagulation factor IX mutations in Chinese hemophilia B patients. | 0 |
| 37678545 | 2023 | Crippling down factor IX for therapeutic gain. | 0 |
| 34412085 | 2022 | Human coagulation factor IX: a systematic review of its characteristics. | 2 |
| 34590426 | 2022 | Molecular analysis of severe hemophilia B in Indian families: Identification of mutational hotspot and novel variants. | 0 |
| 34626083 | 2022 | F9 missense mutations impairing factor IX activation are associated with pleiotropic plasma phenotypes. | 6 |
| 35184131 | 2022 | Genome wide CRISPR/Cas9 screen identifies the coagulation factor IX (F9) as a regulator of senescence. | 11 |
| 35246318 | 2022 | Active factor XI is associated with the risk of cardiovascular events in stable coronary artery disease patients. | 5 |
Citation
Dessen P
F9 (coagulation factor IX)
Atlas Genet Cytogenet Oncol Haematol. 2016-10-01
Online version: http://atlasgeneticsoncology.org/gene/56350/gene-fusions-explorer/gene-explorer/
