SNRPA (small nuclear ribonucleoprotein polypeptide A)

2016-10-01  

Identity

HGNC
LOCATION
19q13.2
LOCUSID
ALIAS
Mud1,U1-A,U1A
FUSION GENES

Other Information

Locus ID:

NCBI: 6626
MIM: 182285
HGNC: 11151
Ensembl: ENSG00000077312

Variants:

dbSNP: 6626
ClinVar: 6626
TCGA: ENSG00000077312
COSMIC: SNRPA

RNA/Proteins

Gene IDTranscript IDUniprot
ENSG00000077312ENST00000243563P09012
ENSG00000077312ENST00000597353M0R2B8
ENSG00000077312ENST00000599362M0R221
ENSG00000077312ENST00000600456M0R0G9
ENSG00000077312ENST00000601253M0QXK2
ENSG00000077312ENST00000601393M0R268
ENSG00000077312ENST00000601545M0QZG7

Expression (GTEx)

0
50
100
150
200

Pathways

PathwaySourceExternal ID
SpliceosomeKEGGko03040
SpliceosomeKEGGhsa03040
Spliceosome, U1-snRNPKEGGhsa_M00351
Spliceosome, U1-snRNPKEGGM00351
Gene ExpressionREACTOMER-HSA-74160
Processing of Capped Intron-Containing Pre-mRNAREACTOMER-HSA-72203
mRNA SplicingREACTOMER-HSA-72172
mRNA Splicing - Major PathwayREACTOMER-HSA-72163

Protein levels (Protein atlas)

Not detected
Low
Medium
High

References

Pubmed IDYearTitleCitations
350984102022Circ_0009910 Serves as miR-361-3p Sponge to Promote the Proliferation, Metastasis, and Glycolysis of Gastric Cancer via Regulating SNRPA.2
350984102022Circ_0009910 Serves as miR-361-3p Sponge to Promote the Proliferation, Metastasis, and Glycolysis of Gastric Cancer via Regulating SNRPA.2
326290402020The Small Nuclear Ribonucleoprotein Polypeptide A (SNRPA) binds to the G-quadruplex of the BAG-1 5'UTR.0
326290402020The Small Nuclear Ribonucleoprotein Polypeptide A (SNRPA) binds to the G-quadruplex of the BAG-1 5'UTR.0
311071492019Nuclear retention element recruits U1 snRNP components to restrain spliced lncRNAs in the nucleus.35
311071492019Nuclear retention element recruits U1 snRNP components to restrain spliced lncRNAs in the nucleus.35
294372352018Exome sequencing reveals three homozygous missense variants in SNRPA in two sisters with syndromic intellectual disability.2
300398892018SNRPA enhances tumour cell growth in gastric cancer through modulating NGF expression.25
294372352018Exome sequencing reveals three homozygous missense variants in SNRPA in two sisters with syndromic intellectual disability.2
300398892018SNRPA enhances tumour cell growth in gastric cancer through modulating NGF expression.25
289548862017Small Nuclear Ribonucleoprotein Polypeptide A-Mediated Alternative Polyadenylation of STAT5B during Th1 Cell Differentiation.8
289548862017Small Nuclear Ribonucleoprotein Polypeptide A-Mediated Alternative Polyadenylation of STAT5B during Th1 Cell Differentiation.8
243620202014U1A regulates 3' processing of the survival motor neuron mRNA.17
243620202014U1A regulates 3' processing of the survival motor neuron mRNA.17
212984552011The small nuclear ribonucleoprotein U1A interacts with NS5 from yellow fever virus.4

Citation

Dessen P

SNRPA (small nuclear ribonucleoprotein polypeptide A)

Atlas Genet Cytogenet Oncol Haematol. 2016-10-01

Online version: http://atlasgeneticsoncology.org/gene/56352/snrpa-(small-nuclear-ribonucleoprotein-polypeptide-a)