Non-annotated gene. Preliminary data : if you are an author who wish to write a full paper/card on this gene, contribute in submission tool
Other Information
Locus ID:
NCBI: 123099
MIM: 610862
HGNC: 20113
Ensembl: ENSG00000168350
Variants:
dbSNP: 123099
ClinVar: 123099
TCGA: ENSG00000168350
COSMIC: DEGS2
RNA/Proteins
| Gene ID | Transcript ID | Uniprot |
|---|---|---|
| ENSG00000168350 | ENST00000305631 | Q6QHC5 |
| ENSG00000168350 | ENST00000553834 | G3V2F9 |
Expression (GTEx)
Pathways
References
| Pubmed ID | Year | Title | Citations |
|---|---|---|---|
| 36907437 | 2023 | Bifunctional DEGS2 has higher hydroxylase activity toward substrates with very-long-chain fatty acids in the production of phytosphingosine ceramides. | 3 |
| 36907437 | 2023 | Bifunctional DEGS2 has higher hydroxylase activity toward substrates with very-long-chain fatty acids in the production of phytosphingosine ceramides. | 3 |
| 25871975 | 2015 | DEGS2 polymorphism associated with cognition in schizophrenia is associated with gene expression in brain. | 13 |
| 25871975 | 2015 | DEGS2 polymorphism associated with cognition in schizophrenia is associated with gene expression in brain. | 13 |
| 21914808 | 2011 | Dihydroceramide-based response to hypoxia. | 37 |
| 21914808 | 2011 | Dihydroceramide-based response to hypoxia. | 37 |
| 20677014 | 2010 | An approach based on a genome-wide association study reveals candidate loci for narcolepsy. | 19 |
| 20677014 | 2010 | An approach based on a genome-wide association study reveals candidate loci for narcolepsy. | 19 |
| 15063729 | 2004 | Identification of the human sphingolipid C4-hydroxylase, hDES2, and its up-regulation during keratinocyte differentiation. | 41 |
| 15063729 | 2004 | Identification of the human sphingolipid C4-hydroxylase, hDES2, and its up-regulation during keratinocyte differentiation. | 41 |
Citation
Dessen P
DEGS2 (delta 4-desaturase, sphingolipid 2)
Atlas Genet Cytogenet Oncol Haematol. 2016-10-01
Online version: http://atlasgeneticsoncology.org/gene/56355/degs2-(delta-4-desaturase-sphingolipid-2)
