Non-annotated gene. Preliminary data : if you are an author who wish to write a full paper/card on this gene, contribute in submission tool
Other Information
Locus ID:
NCBI: 79918
MIM: 616424
HGNC: 26116
Ensembl: ENSG00000103037
Variants:
dbSNP: 79918
ClinVar: 79918
TCGA: ENSG00000103037
COSMIC: SETD6
RNA/Proteins
Expression (GTEx)
Pathways
| Pathway | Source | External ID |
|---|---|---|
| Chromatin organization | REACTOME | R-HSA-4839726 |
| Chromatin modifying enzymes | REACTOME | R-HSA-3247509 |
| PKMTs methylate histone lysines | REACTOME | R-HSA-3214841 |
Protein levels (Protein atlas)
References
| Pubmed ID | Year | Title | Citations |
|---|---|---|---|
| 36604642 | 2023 | Investigating the functional role of SETD6 in lung adenocarcinoma. | 1 |
| 36604642 | 2023 | Investigating the functional role of SETD6 in lung adenocarcinoma. | 1 |
| 35550916 | 2022 | Structure-function conservation between the methyltransferases SETD3 and SETD6. | 1 |
| 35694846 | 2022 | TWIST1 methylation by SETD6 selectively antagonizes LINC-PINT expression in glioma. | 3 |
| 36300937 | 2022 | SETD6 Regulates E2-Dependent Human Papillomavirus Transcription. | 2 |
| 35550916 | 2022 | Structure-function conservation between the methyltransferases SETD3 and SETD6. | 1 |
| 35694846 | 2022 | TWIST1 methylation by SETD6 selectively antagonizes LINC-PINT expression in glioma. | 3 |
| 36300937 | 2022 | SETD6 Regulates E2-Dependent Human Papillomavirus Transcription. | 2 |
| 33710605 | 2021 | Silencing of SETD6 inhibits the tumorigenesis of oral squamous cell carcinoma by inhibiting methylation of PAK4 and RelA. | 2 |
| 34039605 | 2021 | BRD4 methylation by the methyltransferase SETD6 regulates selective transcription to control mRNA translation. | 16 |
| 33710605 | 2021 | Silencing of SETD6 inhibits the tumorigenesis of oral squamous cell carcinoma by inhibiting methylation of PAK4 and RelA. | 2 |
| 34039605 | 2021 | BRD4 methylation by the methyltransferase SETD6 regulates selective transcription to control mRNA translation. | 16 |
| 31370726 | 2020 | Lysine methyltransferase SETD6 modifies histones on a glycine-lysine motif. | 4 |
| 31370726 | 2020 | Lysine methyltransferase SETD6 modifies histones on a glycine-lysine motif. | 4 |
| 30622182 | 2019 | The methyltransferase SETD6 regulates Mitotic progression through PLK1 methylation. | 18 |
Citation
Dessen P
SETD6 (SET domain containing 6, protein lysine methyltransferase)
Atlas Genet Cytogenet Oncol Haematol. 2016-10-01
Online version: http://atlasgeneticsoncology.org/gene/56371/setd6-(set-domain-containing-6-protein-lysine-methyltransferase)
