LRP10 (LDL receptor related protein 10)

2016-10-01  

Identity

HGNC
LOCATION
14q11.2
LOCUSID
ALIAS
LRP-10,LRP9,MST087,MSTP087
FUSION GENES

Other Information

Locus ID:

NCBI: 26020
MIM: 609921
HGNC: 14553
Ensembl: ENSG00000197324

Variants:

dbSNP: 26020
ClinVar: 26020
TCGA: ENSG00000197324
COSMIC: LRP10

RNA/Proteins

Gene IDTranscript IDUniprot
ENSG00000197324ENST00000359591Q7Z4F1
ENSG00000197324ENST00000546834Q7Z4F1
ENSG00000197324ENST00000551466H0YHW7

Expression (GTEx)

0
50
100
150
200
250

Pathways

PathwaySourceExternal ID
Signal TransductionREACTOMER-HSA-162582
Visual phototransductionREACTOMER-HSA-2187338
Retinoid metabolism and transportREACTOMER-HSA-975634
MetabolismREACTOMER-HSA-1430728
Metabolism of vitamins and cofactorsREACTOMER-HSA-196854
Metabolism of fat-soluble vitaminsREACTOMER-HSA-6806667

References

Pubmed IDYearTitleCitations
383154242024LRP10 and α-synuclein transmission in Lewy body diseases.0
383154242024LRP10 and α-synuclein transmission in Lewy body diseases.0
364344762023Genetic analysis of the LRP10 gene in Chinese patients with Parkinson's disease.2
364344762023Genetic analysis of the LRP10 gene in Chinese patients with Parkinson's disease.2
326903422021Rare, pathogenic variants in LRP10 are associated with amyotrophic lateral sclerosis in patients from mainland China.3
329502732021Mutation analysis of LRP10 in a large Chinese familial Parkinson disease cohort.3
331181392021LRP10 Mutations May Correlate with Sporadic Parkinson's Disease in China.1
339130392021LRP10 interacts with SORL1 in the intracellular vesicle trafficking pathway in non-neuronal brain cells and localises to Lewy bodies in Parkinson's disease and dementia with Lewy bodies.10
342169362021Screening of LRP10 mutations in Parkinson's disease patients from Italy.2
342460392021Role of LRP10 in Parkinson's disease in a Taiwanese cohort.1
326903422021Rare, pathogenic variants in LRP10 are associated with amyotrophic lateral sclerosis in patients from mainland China.3
329502732021Mutation analysis of LRP10 in a large Chinese familial Parkinson disease cohort.3
331181392021LRP10 Mutations May Correlate with Sporadic Parkinson's Disease in China.1
339130392021LRP10 interacts with SORL1 in the intracellular vesicle trafficking pathway in non-neuronal brain cells and localises to Lewy bodies in Parkinson's disease and dementia with Lewy bodies.10
342169362021Screening of LRP10 mutations in Parkinson's disease patients from Italy.2

Citation

Dessen P

LRP10 (LDL receptor related protein 10)

Atlas Genet Cytogenet Oncol Haematol. 2016-10-01

Online version: http://atlasgeneticsoncology.org/gene/56379/lrp10-(ldl-receptor-related-protein-10)