Identity
HGNC
LOCATION
7q11.23
LOCUSID
ALIAS
OOMD3,ZP3A,ZP3B,ZPC,Zp-3
FUSION GENES
Non-annotated gene. Preliminary data : if you are an author who wish to write a full paper/card on this gene, contribute in submission tool
Other Information
Locus ID:
NCBI: 7784
MIM: 182889
HGNC: 13189
Ensembl: ENSG00000188372
Variants:
dbSNP: 7784
ClinVar: 7784
TCGA: ENSG00000188372
COSMIC: ZP3
RNA/Proteins
| Gene ID | Transcript ID | Uniprot |
|---|---|---|
| ENSG00000188372 | ENST00000336517 | P21754 |
| ENSG00000188372 | ENST00000394857 | P21754 |
| ENSG00000188372 | ENST00000394860 | H0Y3M4 |
| ENSG00000188372 | ENST00000416245 | E9PFI9 |
Expression (GTEx)
Pathways
| Pathway | Source | External ID |
|---|---|---|
| Reproduction | REACTOME | R-HSA-1474165 |
| Fertilization | REACTOME | R-HSA-1187000 |
| Interaction With The Zona Pellucida | REACTOME | R-HSA-1300644 |
Protein levels (Protein atlas)
References
| Pubmed ID | Year | Title | Citations |
|---|---|---|---|
| 36931917 | 2023 | Novel variants in ZP1, ZP2 and ZP3 associated with empty follicle syndrome and abnormal zona pellucida. | 4 |
| 36931917 | 2023 | Novel variants in ZP1, ZP2 and ZP3 associated with empty follicle syndrome and abnormal zona pellucida. | 4 |
| 34736966 | 2022 | Novel expression of zona pellucida 3 protein in normal testis; potential functional implications. | 4 |
| 34816529 | 2022 | A novel gene mutation in ZP3 loop region identified in patients with empty follicle syndrome. | 4 |
| 35366744 | 2022 | Novel mutations in ZP2 and ZP3 cause female infertility in three patients. | 2 |
| 36335766 | 2022 | Novel mutations in TUBB8 and ZP3 cause human oocyte maturation arrest and female infertility. | 2 |
| 34736966 | 2022 | Novel expression of zona pellucida 3 protein in normal testis; potential functional implications. | 4 |
| 34816529 | 2022 | A novel gene mutation in ZP3 loop region identified in patients with empty follicle syndrome. | 4 |
| 35366744 | 2022 | Novel mutations in ZP2 and ZP3 cause female infertility in three patients. | 2 |
| 36335766 | 2022 | Novel mutations in TUBB8 and ZP3 cause human oocyte maturation arrest and female infertility. | 2 |
| 33140178 | 2021 | A novel mutation in ZP3 causes empty follicle syndrome and abnormal zona pellucida formation. | 14 |
| 33604805 | 2021 | A novel homozygous variant in ZP2 causes abnormal zona pellucida formation and female infertility. | 7 |
| 33140178 | 2021 | A novel mutation in ZP3 causes empty follicle syndrome and abnormal zona pellucida formation. | 14 |
| 33604805 | 2021 | A novel homozygous variant in ZP2 causes abnormal zona pellucida formation and female infertility. | 7 |
| 32569527 | 2020 | Zona Pellucida Proteins, Fibrils, and Matrix. | 24 |
Citation
Dessen P
ZP3 (zona pellucida glycoprotein 3)
Atlas Genet Cytogenet Oncol Haematol. 2016-10-01
Online version: http://atlasgeneticsoncology.org/gene/56382/zp3-(zona-pellucida-glycoprotein-3)
