Non-annotated gene. Preliminary data : if you are an author who wish to write a full paper/card on this gene, contribute in submission tool
Other Information
Locus ID:
NCBI: 1357
MIM: 114850
HGNC: 2296
Ensembl: ENSG00000091704
Variants:
dbSNP: 1357
ClinVar: 1357
TCGA: ENSG00000091704
COSMIC: CPA1
RNA/Proteins
Expression (GTEx)
Pathways
| Pathway | Source | External ID |
|---|---|---|
| Pancreatic secretion | KEGG | ko04972 |
| Pancreatic secretion | KEGG | hsa04972 |
| Protein digestion and absorption | KEGG | ko04974 |
| Protein digestion and absorption | KEGG | hsa04974 |
Protein levels (Protein atlas)
References
| Pubmed ID | Year | Title | Citations |
|---|---|---|---|
| 34774536 | 2022 | Enhanced carboxypeptidase efficacies and differentiation of peptide epimers. | 2 |
| 34817877 | 2022 | Endoplasmic stress-inducing variants in CPB1 and CPA1 and risk of pancreatic cancer: A case-control study and meta-analysis. | 6 |
| 34889867 | 2022 | Carboxypeptidase A1 (CPA1) Immunohistochemistry Is Highly Sensitive and Specific for Acinar Cell Carcinoma (ACC) of the Pancreas. | 9 |
| 36555104 | 2022 | Novel p.G250A Mutation Associated with Chronic Pancreatitis Highlights Misfolding-Prone Region in Carboxypeptidase A1 (CPA1). | 1 |
| 34774536 | 2022 | Enhanced carboxypeptidase efficacies and differentiation of peptide epimers. | 2 |
| 34817877 | 2022 | Endoplasmic stress-inducing variants in CPB1 and CPA1 and risk of pancreatic cancer: A case-control study and meta-analysis. | 6 |
| 34889867 | 2022 | Carboxypeptidase A1 (CPA1) Immunohistochemistry Is Highly Sensitive and Specific for Acinar Cell Carcinoma (ACC) of the Pancreas. | 9 |
| 36555104 | 2022 | Novel p.G250A Mutation Associated with Chronic Pancreatitis Highlights Misfolding-Prone Region in Carboxypeptidase A1 (CPA1). | 1 |
| 32702400 | 2020 | Carboxypeptidase A1 and regenerating islet-derived 1α as new markers for pancreatic acinar cell carcinoma. | 6 |
| 32702400 | 2020 | Carboxypeptidase A1 and regenerating islet-derived 1α as new markers for pancreatic acinar cell carcinoma. | 6 |
| 29669919 | 2018 | Mutations in the pancreatic secretory enzymes CPA1 and CPB1 are associated with pancreatic cancer. | 37 |
| 29669919 | 2018 | Mutations in the pancreatic secretory enzymes CPA1 and CPB1 are associated with pancreatic cancer. | 37 |
| 28497564 | 2017 | No significant enrichment of rare functionally defective CPA1 variants in a large Chinese idiopathic chronic pancreatitis cohort. | 11 |
| 28497564 | 2017 | No significant enrichment of rare functionally defective CPA1 variants in a large Chinese idiopathic chronic pancreatitis cohort. | 11 |
| 27358403 | 2016 | Complex Formation of Human Proelastases with Procarboxypeptidases A1 and A2. | 18 |
Citation
Dessen P
CPA1 (carboxypeptidase A1)
Atlas Genet Cytogenet Oncol Haematol. 2016-10-01
Online version: http://atlasgeneticsoncology.org/gene/56385/cpa1-(carboxypeptidase-a1)
