Non-annotated gene. Preliminary data : if you are an author who wish to write a full paper/card on this gene, contribute in submission tool
Other Information
Locus ID:
NCBI: 54552
MIM: 300873
HGNC: 25553
Ensembl: ENSG00000130119
Variants:
dbSNP: 54552
ClinVar: 54552
TCGA: ENSG00000130119
COSMIC: GNL3L
RNA/Proteins
Expression (GTEx)
Pathways
| Pathway | Source | External ID |
|---|---|---|
| Ribosome biogenesis in eukaryotes | KEGG | ko03008 |
| Ribosome biogenesis in eukaryotes | KEGG | hsa03008 |
Protein levels (Protein atlas)
References
| Pubmed ID | Year | Title | Citations |
|---|---|---|---|
| 38022822 | 2023 | Knockdown of GNL3L Alleviates the Progression of COPD Through Inhibiting the ATM/p53 Pathway. | 0 |
| 38148364 | 2023 | GNL3L promotes autophagy via regulating AMPK signaling in esophageal cancer cells. | 2 |
| 38022822 | 2023 | Knockdown of GNL3L Alleviates the Progression of COPD Through Inhibiting the ATM/p53 Pathway. | 0 |
| 38148364 | 2023 | GNL3L promotes autophagy via regulating AMPK signaling in esophageal cancer cells. | 2 |
| 34032716 | 2021 | High expression of guanine nucleotide-binding protein-like-3-like is associated with poor prognosis in esophageal cancer. | 3 |
| 34032716 | 2021 | High expression of guanine nucleotide-binding protein-like-3-like is associated with poor prognosis in esophageal cancer. | 3 |
| 27764577 | 2016 | Leucine Zipper Down-regulated in Cancer-1 (LDOC1) interacts with Guanine nucleotide binding protein-like 3-like (GNL3L) to modulate Nuclear Factor-kappa B (NF-κB) signaling during cell proliferation. | 19 |
| 27764577 | 2016 | Leucine Zipper Down-regulated in Cancer-1 (LDOC1) interacts with Guanine nucleotide binding protein-like 3-like (GNL3L) to modulate Nuclear Factor-kappa B (NF-κB) signaling during cell proliferation. | 19 |
| 26274615 | 2015 | GNL3L Is a Nucleo-Cytoplasmic Shuttling Protein: Role in Cell Cycle Regulation. | 13 |
| 26274615 | 2015 | GNL3L Is a Nucleo-Cytoplasmic Shuttling Protein: Role in Cell Cycle Regulation. | 13 |
| 24610951 | 2014 | Nucleostemin and GNL3L exercise distinct functions in genome protection and ribosome synthesis, respectively. | 26 |
| 24610951 | 2014 | Nucleostemin and GNL3L exercise distinct functions in genome protection and ribosome synthesis, respectively. | 26 |
| 21063916 | 2011 | Continual expression throughout the cell cycle and downregulation upon adipogenic differentiation makes nucleostemin a vital human MSC proliferation marker. | 8 |
| 21132010 | 2011 | GNL3L depletion destabilizes MDM2 and induces p53-dependent G2/M arrest. | 23 |
| 21063916 | 2011 | Continual expression throughout the cell cycle and downregulation upon adipogenic differentiation makes nucleostemin a vital human MSC proliferation marker. | 8 |
Citation
Dessen P
GNL3L (G protein nucleolar 3 like)
Atlas Genet Cytogenet Oncol Haematol. 2016-10-01
Online version: http://atlasgeneticsoncology.org/gene/56386/gene-fusions/meetings/
