Non-annotated gene. Preliminary data : if you are an author who wish to write a full paper/card on this gene, contribute in submission tool
Other Information
Locus ID:
NCBI: 1880
MIM: 605741
HGNC: 3128
Ensembl: ENSG00000169508
Variants:
dbSNP: 1880
ClinVar: 1880
TCGA: ENSG00000169508
COSMIC: GPR183
RNA/Proteins
| Gene ID | Transcript ID | Uniprot |
|---|---|---|
| ENSG00000169508 | ENST00000376414 | P32249 |
| ENSG00000169508 | ENST00000376414 | A0A024RDX2 |
Expression (GTEx)
Pathways
| Pathway | Source | External ID |
|---|---|---|
| Signal Transduction | REACTOME | R-HSA-162582 |
| Signaling by GPCR | REACTOME | R-HSA-372790 |
| GPCR ligand binding | REACTOME | R-HSA-500792 |
| Class A/1 (Rhodopsin-like receptors) | REACTOME | R-HSA-373076 |
Protein levels (Protein atlas)
References
| Pubmed ID | Year | Title | Citations |
|---|---|---|---|
| 38770825 | 2024 | The EBI2 receptor is coexpressed with CCR5 in CD4 + T cells and boosts HIV-1 R5 replication. | 0 |
| 38877985 | 2024 | Exploring the Activation Mechanism of the GPR183 Receptor. | 0 |
| 38770825 | 2024 | The EBI2 receptor is coexpressed with CCR5 in CD4 + T cells and boosts HIV-1 R5 replication. | 0 |
| 38877985 | 2024 | Exploring the Activation Mechanism of the GPR183 Receptor. | 0 |
| 37469011 | 2023 | The Oxysterol Receptor EBI2 Links Innate and Adaptive Immunity to Limit IFN Response and Systemic Lupus Erythematosus. | 1 |
| 37469011 | 2023 | The Oxysterol Receptor EBI2 Links Innate and Adaptive Immunity to Limit IFN Response and Systemic Lupus Erythematosus. | 1 |
| 35351968 | 2022 | EBI2 is a negative modulator of brown adipose tissue energy expenditure in mice and human brown adipocytes. | 2 |
| 35875859 | 2022 | Abnormal lower expression of GPR183 in peripheral blood T and B cell subsets of systemic lupus erythematosus patients. | 2 |
| 35351968 | 2022 | EBI2 is a negative modulator of brown adipose tissue energy expenditure in mice and human brown adipocytes. | 2 |
| 35875859 | 2022 | Abnormal lower expression of GPR183 in peripheral blood T and B cell subsets of systemic lupus erythematosus patients. | 2 |
| 33511653 | 2021 | A single nucleotide polymorphism in the gene for GPR183 increases its surface expression on blood lymphocytes of patients with inflammatory bowel disease. | 4 |
| 34229205 | 2021 | EBI2-expressing B cells in neuromyelitis optica spectrum disorder with AQP4-IgG: Association with acute attacks and serum cytokines. | 1 |
| 33511653 | 2021 | A single nucleotide polymorphism in the gene for GPR183 increases its surface expression on blood lymphocytes of patients with inflammatory bowel disease. | 4 |
| 34229205 | 2021 | EBI2-expressing B cells in neuromyelitis optica spectrum disorder with AQP4-IgG: Association with acute attacks and serum cytokines. | 1 |
| 31550518 | 2020 | Orphan G-protein coupled receptor 183 (GPR183) potentiates insulin secretion and prevents glucotoxicity-induced β-cell dysfunction. | 9 |
Citation
Dessen P
GPR183 (G protein-coupled receptor 183)
Atlas Genet Cytogenet Oncol Haematol. 2016-10-01
Online version: http://atlasgeneticsoncology.org/gene/56392/
