RNASE3 (ribonuclease A family member 3)

2016-10-01  

Identity

HGNC
LOCATION
14q11.2
LOCUSID
ALIAS
ECP,RAF1,RNS3

Other Information

Locus ID:

NCBI: 6037
MIM: 131398
HGNC: 10046
Ensembl: ENSG00000169397

Variants:

dbSNP: 6037
ClinVar: 6037
TCGA: ENSG00000169397
COSMIC: RNASE3

RNA/Proteins

Gene IDTranscript IDUniprot
ENSG00000169397ENST00000304639P12724

Expression (GTEx)

0
5
10
15
20
25
30
35
40

Pathways

PathwaySourceExternal ID
AsthmaKEGGko05310
AsthmaKEGGhsa05310
Immune SystemREACTOMER-HSA-168256
Innate Immune SystemREACTOMER-HSA-168249
Antimicrobial peptidesREACTOMER-HSA-6803157
Neutrophil degranulationREACTOMER-HSA-6798695

Protein levels (Protein atlas)

Not detected
Low
Medium
High

References

Pubmed IDYearTitleCitations
385631712024[The auxiliary diagnostic value of ECP and MPO expression in nasal secretions in different types of rhinitis].0
385631712024[The auxiliary diagnostic value of ECP and MPO expression in nasal secretions in different types of rhinitis].0
345154562023Eosinophilic cationic protein (ECP) in the clinical work-up of chronic cough.1
380331682023Variants of IL6, IL10, FCN2, RNASE3, IL12B and IL17B loci are associated with Schistosoma mansoni worm burden in the Albert Nile region of Uganda.0
345154562023Eosinophilic cationic protein (ECP) in the clinical work-up of chronic cough.1
380331682023Variants of IL6, IL10, FCN2, RNASE3, IL12B and IL17B loci are associated with Schistosoma mansoni worm burden in the Albert Nile region of Uganda.0
346157362022Blood eosinophil cationic protein and eosinophil-derived neurotoxin are associated with different asthma expression and evolution in adults.8
346157362022Blood eosinophil cationic protein and eosinophil-derived neurotoxin are associated with different asthma expression and evolution in adults.8
327618772021Serum eosinophil cationic protein: a prognostic factor for early postoperative recurrence of nasal polyps.6
332264402021Human RNase3 immune modulation by catalytic-dependent and independent modes in a macrophage-cell line infection model.5
327618772021Serum eosinophil cationic protein: a prognostic factor for early postoperative recurrence of nasal polyps.6
332264402021Human RNase3 immune modulation by catalytic-dependent and independent modes in a macrophage-cell line infection model.5
324427012020Eosinophil cationic protein is a potential surrogate marker of allergic contact dermatitis: A single-center, retrospective study of 216 patients.3
331130802020Haplotype of RNASE 3 polymorphisms is associated with severe malaria in an Indian population.1
324427012020Eosinophil cationic protein is a potential surrogate marker of allergic contact dermatitis: A single-center, retrospective study of 216 patients.3

Citation

Dessen P

RNASE3 (ribonuclease A family member 3)

Atlas Genet Cytogenet Oncol Haematol. 2016-10-01

Online version: http://atlasgeneticsoncology.org/gene/56394/rnase3-(ribonuclease-a-family-member-3)