Identity
HGNC
LOCATION
19p13.13
LOCUSID
ALIAS
DHS,DS,MIG13,NEDSSWI
FUSION GENES
Non-annotated gene. Preliminary data : if you are an author who wish to write a full paper/card on this gene, contribute in submission tool
Other Information
Locus ID:
NCBI: 1725
MIM: 600944
HGNC: 2869
Ensembl: ENSG00000095059
Variants:
dbSNP: 1725
ClinVar: 1725
TCGA: ENSG00000095059
COSMIC: DHPS
RNA/Proteins
Expression (GTEx)
Pathways
Protein levels (Protein atlas)
References
| Pubmed ID | Year | Title | Citations |
|---|---|---|---|
| 37925109 | 2024 | Clinical significance of mutations in dihydropteroate synthase in Pneumocystis jirovecii pneumonia among non-HIV-infected patients. | 0 |
| 37925109 | 2024 | Clinical significance of mutations in dihydropteroate synthase in Pneumocystis jirovecii pneumonia among non-HIV-infected patients. | 0 |
| 36973244 | 2023 | Cryo-EM structure of human eIF5A-DHS complex reveals the molecular basis of hypusination-associated neurodegenerative disorders. | 3 |
| 37333770 | 2023 | Deoxyhypusine synthase mutations alter the post-translational modification of eukaryotic initiation factor 5A resulting in impaired human and mouse neural homeostasis. | 1 |
| 36973244 | 2023 | Cryo-EM structure of human eIF5A-DHS complex reveals the molecular basis of hypusination-associated neurodegenerative disorders. | 3 |
| 37333770 | 2023 | Deoxyhypusine synthase mutations alter the post-translational modification of eukaryotic initiation factor 5A resulting in impaired human and mouse neural homeostasis. | 1 |
| 34947982 | 2021 | eIF5A-Independent Role of DHPS in p21(CIP1) and Cell Fate Regulation. | 2 |
| 34947982 | 2021 | eIF5A-Independent Role of DHPS in p21(CIP1) and Cell Fate Regulation. | 2 |
| 32235505 | 2020 | Half Way to Hypusine-Structural Basis for Substrate Recognition by Human Deoxyhypusine Synthase. | 13 |
| 32235505 | 2020 | Half Way to Hypusine-Structural Basis for Substrate Recognition by Human Deoxyhypusine Synthase. | 13 |
| 30661771 | 2019 | Recessive Rare Variants in Deoxyhypusine Synthase, an Enzyme Involved in the Synthesis of Hypusine, Are Associated with a Neurodevelopmental Disorder. | 23 |
| 31558321 | 2019 | DHPS-dependent hypusination of eIF5A1/2 is necessary for TGFβ/fibronectin-induced breast cancer metastasis and associates with prognostically unfavorable genomic alterations in TP53. | 3 |
| 30661771 | 2019 | Recessive Rare Variants in Deoxyhypusine Synthase, an Enzyme Involved in the Synthesis of Hypusine, Are Associated with a Neurodevelopmental Disorder. | 23 |
| 31558321 | 2019 | DHPS-dependent hypusination of eIF5A1/2 is necessary for TGFβ/fibronectin-induced breast cancer metastasis and associates with prognostically unfavorable genomic alterations in TP53. | 3 |
| 27041563 | 2016 | The hypusine cascade promotes cancer progression and metastasis through the regulation of RhoA in squamous cell carcinoma. | 19 |
Citation
Dessen P
DHPS (deoxyhypusine synthase)
Atlas Genet Cytogenet Oncol Haematol. 2016-10-01
Online version: http://atlasgeneticsoncology.org/gene/56398/dhps-(deoxyhypusine-synthase)
