Identity
HGNC
LOCATION
1p36.12
LOCUSID
ALIAS
C1orf166,GIDE,MAPL,MULAN,RNF218
FUSION GENES
Non-annotated gene. Preliminary data : if you are an author who wish to write a full paper/card on this gene, contribute in submission tool
Other Information
Locus ID:
NCBI: 79594
MIM: 612037
HGNC: 25762
Ensembl: ENSG00000090432
Variants:
dbSNP: 79594
ClinVar: 79594
TCGA: ENSG00000090432
COSMIC: MUL1
RNA/Proteins
| Gene ID | Transcript ID | Uniprot |
|---|---|---|
| ENSG00000090432 | ENST00000264198 | Q969V5 |
| ENSG00000090432 | ENST00000264198 | A0A024RAA0 |
Expression (GTEx)
Pathways
References
| Pubmed ID | Year | Title | Citations |
|---|---|---|---|
| 33069830 | 2021 | A risk signature of three autophagy-related genes for predicting lower grade glioma survival is associated with tumor immune microenvironment. | 11 |
| 34322908 | 2021 | A new functional role of mitochondria-anchored protein ligase in peroxisome morphology in mammalian cells. | 8 |
| 33069830 | 2021 | A risk signature of three autophagy-related genes for predicting lower grade glioma survival is associated with tumor immune microenvironment. | 11 |
| 34322908 | 2021 | A new functional role of mitochondria-anchored protein ligase in peroxisome morphology in mammalian cells. | 8 |
| 31929179 | 2020 | The RING domain of mitochondrial E3 ubiquitin ligase 1 and its complex with Ube2D2: crystallization and X-ray diffraction. | 3 |
| 32005965 | 2020 | Mitochondrial MUL1 E3 ubiquitin ligase regulates Hypoxia Inducible Factor (HIF-1α) and metabolic reprogramming by modulating the UBXN7 cofactor protein. | 14 |
| 31929179 | 2020 | The RING domain of mitochondrial E3 ubiquitin ligase 1 and its complex with Ube2D2: crystallization and X-ray diffraction. | 3 |
| 32005965 | 2020 | Mitochondrial MUL1 E3 ubiquitin ligase regulates Hypoxia Inducible Factor (HIF-1α) and metabolic reprogramming by modulating the UBXN7 cofactor protein. | 14 |
| 30793286 | 2019 | MUL1 gene polymorphisms and Parkinson's disease risk. | 3 |
| 31235254 | 2019 | Solution structure of MUL1-RING domain and its interaction with p53 transactivation domain. | 6 |
| 30793286 | 2019 | MUL1 gene polymorphisms and Parkinson's disease risk. | 3 |
| 31235254 | 2019 | Solution structure of MUL1-RING domain and its interaction with p53 transactivation domain. | 6 |
| 29260979 | 2018 | HSPA5 negatively regulates lysosomal activity through ubiquitination of MUL1 in head and neck cancer. | 38 |
| 29260979 | 2018 | HSPA5 negatively regulates lysosomal activity through ubiquitination of MUL1 in head and neck cancer. | 38 |
| 28273895 | 2017 | The dynamic interacting landscape of MAPL reveals essential functions for SUMOylation in innate immunity. | 16 |
Citation
Dessen P
MUL1 (mitochondrial E3 ubiquitin protein ligase 1)
Atlas Genet Cytogenet Oncol Haematol. 2016-10-01
Online version: http://atlasgeneticsoncology.org/gene/56405/mul1-(mitochondrial-e3-ubiquitin-protein-ligase-1)
