Identity
HGNC
LOCATION
6p24.2
LOCUSID
ALIAS
ERVFRDE1,GLLL6191,HERV-FRD,HERV-W/FRD,UNQ6191,envFRD
FUSION GENES
Non-annotated gene. Preliminary data : if you are an author who wish to write a full paper/card on this gene, contribute in submission tool
Other Information
Locus ID:
NCBI: 405754
MIM: 610524
HGNC: 33823
Ensembl: ENSG00000244476
Variants:
dbSNP: 405754
ClinVar: 405754
TCGA: ENSG00000244476
COSMIC: ERVFRD-1
RNA/Proteins
| Gene ID | Transcript ID | Uniprot |
|---|---|---|
| ENSG00000244476 | ENST00000472091 | P60508 |
| ENSG00000244476 | ENST00000542862 | P60508 |
Expression (GTEx)
References
| Pubmed ID | Year | Title | Citations |
|---|---|---|---|
| 36768581 | 2023 | Interaction between Long Noncoding RNAs and Syncytin-1/Syncytin-2 Genes and Transcripts: How Noncoding RNAs May Affect Pregnancy in Patients with Systemic Lupus Erythematosus. | 1 |
| 37695891 | 2023 | Transgenic expression of the HERV-W envelope protein leads to polarized glial cell populations and a neurodegenerative environment. | 2 |
| 36768581 | 2023 | Interaction between Long Noncoding RNAs and Syncytin-1/Syncytin-2 Genes and Transcripts: How Noncoding RNAs May Affect Pregnancy in Patients with Systemic Lupus Erythematosus. | 1 |
| 37695891 | 2023 | Transgenic expression of the HERV-W envelope protein leads to polarized glial cell populations and a neurodegenerative environment. | 2 |
| 35710838 | 2022 | Structural insights into the lysophospholipid brain uptake mechanism and its inhibition by syncytin-2. | 15 |
| 35710838 | 2022 | Structural insights into the lysophospholipid brain uptake mechanism and its inhibition by syncytin-2. | 15 |
| 33993053 | 2021 | HERV-W envelope expression in blood leukocytes as a marker of disease severity of COVID-19. | 8 |
| 33993053 | 2021 | HERV-W envelope expression in blood leukocytes as a marker of disease severity of COVID-19. | 8 |
| 31318021 | 2020 | Endogenous retrovirus-encoded Syncytin-2 contributes to exosome-mediated immunosuppression of T cells†. | 43 |
| 32145327 | 2020 | Expression of the syncytin-1 and syncytin-2 genes in the trophoblastic tissue of the early pregnancy losses with normal and abnormal karyotypes. | 4 |
| 31318021 | 2020 | Endogenous retrovirus-encoded Syncytin-2 contributes to exosome-mediated immunosuppression of T cells†. | 43 |
| 32145327 | 2020 | Expression of the syncytin-1 and syncytin-2 genes in the trophoblastic tissue of the early pregnancy losses with normal and abnormal karyotypes. | 4 |
| 29750965 | 2018 | A tag SNP in syncytin-2 3-UTR significantly correlates with the risk of severe preeclampsia. | 5 |
| 29750965 | 2018 | A tag SNP in syncytin-2 3-UTR significantly correlates with the risk of severe preeclampsia. | 5 |
| 26853155 | 2016 | Effects of individually silenced N-glycosylation sites and non-synonymous single-nucleotide polymorphisms on the fusogenic function of human syncytin-2. | 6 |
Citation
Dessen P
ERVFRD-1 (endogenous retrovirus group FRD member 1, envelope)
Atlas Genet Cytogenet Oncol Haematol. 2016-10-01
Online version: http://atlasgeneticsoncology.org/gene/56408/ervfrd-1-(endogenous-retrovirus-group-frd-member-1-envelope)
