LRRN3 (leucine rich repeat neuronal 3)

2016-10-01  

Identity

HGNC
LRRN3
LOCATION
7q31.1
LOCUSID
54674
ALIAS
FIGLER5,NLRR-3,NLRR3

Other Information

Locus ID:

NCBI: 54674
HGNC: 17200
Ensembl: ENSG00000173114

Variants:

dbSNP: 54674
ClinVar: 54674
TCGA: ENSG00000173114
COSMIC: LRRN3

RNA/Proteins

Gene IDTranscript IDUniprot
ENSG00000173114ENST00000308478Q9H3W5
ENSG00000173114ENST00000308478A4D0T1
ENSG00000173114ENST00000421101E7EW58
ENSG00000173114ENST00000422987Q9H3W5
ENSG00000173114ENST00000422987A4D0T1
ENSG00000173114ENST00000451085Q9H3W5
ENSG00000173114ENST00000451085A4D0T1

Expression (GTEx)

0
5
10
15
20
25
30
35
Adipose - Subcutaneous
Adipose - Visceral
Adrenal Gland
Artery - Aorta
Artery - Tibial
Bladder
Brain - Amygdala
Brain - Anterior cingulate cortex
Brain - Caudate
Brain - Cerebellar Hemisphere
Brain - Cerebellum
Brain - Cortex
Brain - Frontal Cortex
Brain - Hippocampus
Brain - Hypothalamus
Brain - Nucleus accumbens
Brain - Putamen
Brain - Spinal cord
Brain - Substantia nigra
Breast - Mammary Tissue
Cells - Cultured fibroblasts
Cells - EBV - transformed lymphocytes
Cervix - Ectocervix
Cervix - Endocervix
Colon - Sigmoid
Colon - Transverse
Esophagus - Gastroesophageal Junction
Esophagus - Mucosa
Esophagus - Muscularis
Fallopian Tube
Heart - Atrial Appendage
Heart - Left Ventricle
Kidney - Cortex
Kidney - Medulla
Liver
Lung
Minor Salivary Gland
Muscle - Skeletal
Nerve - Tibial
Ovary
Pancreas
Pituitary
Prostate
Skin - Not Sun Exposed
Skin - Sun Exposed
Small Intestine - Terminal Ileum
Spleen
Stomach
Testis
Thyroid
Uterus
Vagina
Whole Blood

Protein levels (Protein atlas)

Not detected
Low
Medium
High
cerebral cortex
cerebellum
hippocampus
caudate
thyroid gland
adrenal gland
nasopharynx
bronchus
lung
oral mucosa
salivary gland
esophagus
stomach 1
stomach 2
duodenum
small intestine
colon
rectum
liver
gallbladder
pancreas
kidney
urinary bladder
testis
epididymis
seminal vesicle
prostate
vagina
ovary
fallopian tube
endometrium 1
endometrium 2
cervix, uterine
placenta
breast
heart muscle
smooth muscle
skeletal muscle
soft tissue 1
soft tissue 2
adipose tissue
skin 1
skin 2
appendix
spleen
lymph node
tonsil
bone marrow

References

Pubmed IDYearTitleCitations
252567442014Intracellular fragment of NLRR3 (NLRR3-ICD) stimulates ATRA-dependent neuroblastoma differentiation.2
252567442014Intracellular fragment of NLRR3 (NLRR3-ICD) stimulates ATRA-dependent neuroblastoma differentiation.2
219085752011Expression of NLRR3 orphan receptor gene is negatively regulated by MYCN and Miz-1, and its downregulation is associated with unfavorable outcome in neuroblastoma.12
219085752011Expression of NLRR3 orphan receptor gene is negatively regulated by MYCN and Miz-1, and its downregulation is associated with unfavorable outcome in neuroblastoma.12
203796142010Personalized smoking cessation: interactions between nicotine dose, dependence and quit-success genotype score.78
206782492010Polymorphisms in leucine-rich repeat genes are associated with autism spectrum disorder susceptibility in populations of European ancestry.25
203796142010Personalized smoking cessation: interactions between nicotine dose, dependence and quit-success genotype score.78
206782492010Polymorphisms in leucine-rich repeat genes are associated with autism spectrum disorder susceptibility in populations of European ancestry.25

Citation

Dessen P

LRRN3 (leucine rich repeat neuronal 3)

Atlas Genet Cytogenet Oncol Haematol. 2016-10-01

Online version: http://atlasgeneticsoncology.org/gene/56417/lrrn3-(leucine-rich-repeat-neuronal-3)