IFT20 (intraflagellar transport 20)

2016-10-01  

Identity

HGNC
LOCATION
17q11.2
LOCUSID
ALIAS
-
FUSION GENES

Other Information

Locus ID:

NCBI: 90410
MIM: 614394
HGNC: 30989
Ensembl: ENSG00000109083

Variants:

dbSNP: 90410
ClinVar: 90410
TCGA: ENSG00000109083
COSMIC: IFT20

RNA/Proteins

Gene IDTranscript IDUniprot
ENSG00000109083ENST00000357896Q8IY31
ENSG00000109083ENST00000395418Q8IY31
ENSG00000109083ENST00000395418A0A024QZ08
ENSG00000109083ENST00000577498J3KRU2
ENSG00000109083ENST00000578009J3QRH2
ENSG00000109083ENST00000578122J3QRC6
ENSG00000109083ENST00000578985J3QR43
ENSG00000109083ENST00000579419Q8IY31
ENSG00000109083ENST00000585089Q8IY31
ENSG00000109083ENST00000585313Q8IY31
ENSG00000109083ENST00000585313A0A024QZ08
ENSG00000109083ENST00000588477A0A087X2B4

Expression (GTEx)

0
10
20
30
40
50
60
70

Pathways

PathwaySourceExternal ID
Organelle biogenesis and maintenanceREACTOMER-HSA-1852241
Cilium AssemblyREACTOMER-HSA-5617833
Intraflagellar transportREACTOMER-HSA-5620924

Protein levels (Protein atlas)

Not detected
Low
Medium
High

References

Pubmed IDYearTitleCitations
358694902022Associations of IFT20 and GM130 protein expressions with clinicopathological features and survival of patients with lung adenocarcinoma.2
358694902022Associations of IFT20 and GM130 protein expressions with clinicopathological features and survival of patients with lung adenocarcinoma.2
311428072020The intraflagellar transport protein IFT20 controls lysosome biogenesis by regulating the post-Golgi transport of acid hydrolases.21
311428072020The intraflagellar transport protein IFT20 controls lysosome biogenesis by regulating the post-Golgi transport of acid hydrolases.21
307427412019Intraflagellar transport 20 promotes collective cancer cell invasion by regulating polarized organization of Golgi-associated microtubules.11
307427412019Intraflagellar transport 20 promotes collective cancer cell invasion by regulating polarized organization of Golgi-associated microtubules.11
290405582018Constitutively-active FGFR3 disrupts primary cilium length and IFT20 trafficking in various chondrocyte models of achondroplasia.17
292377192018IFT20 modulates ciliary PDGFRα signaling by regulating the stability of Cbl E3 ubiquitin ligases.38
290405582018Constitutively-active FGFR3 disrupts primary cilium length and IFT20 trafficking in various chondrocyte models of achondroplasia.17
292377192018IFT20 modulates ciliary PDGFRα signaling by regulating the stability of Cbl E3 ubiquitin ligases.38
281541592017The T cell IFT20 interactome reveals new players in immune synapse assembly.18
281541592017The T cell IFT20 interactome reveals new players in immune synapse assembly.18
267157562016IFT20 controls LAT recruitment to the immune synapse and T-cell activation in vivo.33
267157562016IFT20 controls LAT recruitment to the immune synapse and T-cell activation in vivo.33
167750042006The intraflagellar transport protein IFT20 is associated with the Golgi complex and is required for cilia assembly.291

Citation

Dessen P

IFT20 (intraflagellar transport 20)

Atlas Genet Cytogenet Oncol Haematol. 2016-10-01

Online version: http://atlasgeneticsoncology.org/gene/56430/ift20-(intraflagellar-transport-20)