ATG14 (autophagy related 14)

2016-10-01  

Identity

HGNC
LOCATION
14q22.3
LOCUSID
ALIAS
ATG14L,BARKOR,KIAA0831
FUSION GENES

Other Information

Locus ID:

NCBI: 22863
MIM: 613515
HGNC: 19962
Ensembl: ENSG00000126775

Variants:

dbSNP: 22863
ClinVar: 22863
TCGA: ENSG00000126775
COSMIC: ATG14

RNA/Proteins

Gene IDTranscript IDUniprot
ENSG00000126775ENST00000247178Q6ZNE5

Expression (GTEx)

0
5
10
15
20
25
30
35

Pathways

PathwaySourceExternal ID
Autophagy - animalKEGGko04140
Autophagy - animalKEGGhsa04140
Cellular responses to stressREACTOMER-HSA-2262752
MacroautophagyREACTOMER-HSA-1632852

Protein levels (Protein atlas)

Not detected
Low
Medium
High

References

Pubmed IDYearTitleCitations
370431092024KLF15 Transcriptionally Activates ATG14 to Promote Autophagy and Attenuate Damage of ox-LDL-Induced HAECs.1
379152532024Control of ATG14 solubility and autophagy by MARCHF7/MARCH7-mediated ubiquitination.1
370431092024KLF15 Transcriptionally Activates ATG14 to Promote Autophagy and Attenuate Damage of ox-LDL-Induced HAECs.1
379152532024Control of ATG14 solubility and autophagy by MARCHF7/MARCH7-mediated ubiquitination.1
377414342023ATG14 plays a critical role in hepatic lipid droplet homeostasis.0
377414342023ATG14 plays a critical role in hepatic lipid droplet homeostasis.0
350667802022CircCBFB is a mediator of hepatocellular carcinoma cell autophagy and proliferation through miR-424-5p/ATG14 axis.4
350667802022CircCBFB is a mediator of hepatocellular carcinoma cell autophagy and proliferation through miR-424-5p/ATG14 axis.4
336192462021HIF-1α-induced expression of m6A reader YTHDF1 drives hypoxia-induced autophagy and malignancy of hepatocellular carcinoma by promoting ATG2A and ATG14 translation.134
337947262021ATG14 and RB1CC1 play essential roles in maintaining muscle homeostasis.3
343088502021[MicroRNA-424 inhibits autophagy and proliferation of hepatocellular carcinoma cells by targeting ATG14].2
344409102021SNAP47 Interacts with ATG14 to Promote VP1 Conjugation and CVB3 Propagation.2
346706642021[miR-148b-3p inhibits the proliferation and autophagy of acute myeloid leukemia cells by targeting ATG14].3
349303442021Down-regulation of circ_0058058 suppresses proliferation, angiogenesis and metastasis in multiple myeloma through miR-338-3p/ATG14 pathway.5
336192462021HIF-1α-induced expression of m6A reader YTHDF1 drives hypoxia-induced autophagy and malignancy of hepatocellular carcinoma by promoting ATG2A and ATG14 translation.134

Citation

Dessen P

ATG14 (autophagy related 14)

Atlas Genet Cytogenet Oncol Haematol. 2016-10-01

Online version: http://atlasgeneticsoncology.org/gene/56434/atg14-(autophagy-related-14)