Non-annotated gene. Preliminary data : if you are an author who wish to write a full paper/card on this gene, contribute in submission tool
Other Information
Locus ID:
NCBI: 147912
MIM: 600963
HGNC: 10891
Ensembl: ENSG00000177045
Variants:
dbSNP: 147912
ClinVar: 147912
TCGA: ENSG00000177045
COSMIC: SIX5
RNA/Proteins
| Gene ID | Transcript ID | Uniprot |
|---|---|---|
| ENSG00000177045 | ENST00000317578 | Q8N196 |
| ENSG00000177045 | ENST00000560160 | H0YLK1 |
| ENSG00000177045 | ENST00000560168 | H0YLF6 |
| ENSG00000177045 | ENST00000622857 | A0A087WXX3 |
Expression (GTEx)
Protein levels (Protein atlas)
References
| Pubmed ID | Year | Title | Citations |
|---|---|---|---|
| 35046468 | 2022 | Phenotype-genotype correlation in patients with typical and atypical branchio-oto-renal syndrome. | 4 |
| 35046468 | 2022 | Phenotype-genotype correlation in patients with typical and atypical branchio-oto-renal syndrome. | 4 |
| 27821176 | 2016 | The expression profile and clinic significance of the SIX family in non-small cell lung cancer. | 44 |
| 27821176 | 2016 | The expression profile and clinic significance of the SIX family in non-small cell lung cancer. | 44 |
| 24730701 | 2014 | Branchio-oto-renal syndrome: comprehensive review based on nationwide surveillance in Japan. | 23 |
| 24730701 | 2014 | Branchio-oto-renal syndrome: comprehensive review based on nationwide surveillance in Japan. | 23 |
| 22447252 | 2012 | Mutation screening of the EYA1, SIX1, and SIX5 genes in an East Asian cohort with branchio-oto-renal syndrome. | 13 |
| 22447252 | 2012 | Mutation screening of the EYA1, SIX1, and SIX5 genes in an East Asian cohort with branchio-oto-renal syndrome. | 13 |
| 21280147 | 2011 | Mutation screening of the EYA1, SIX1, and SIX5 genes in a large cohort of patients harboring branchio-oto-renal syndrome calls into question the pathogenic role of SIX5 mutations. | 43 |
| 21280147 | 2011 | Mutation screening of the EYA1, SIX1, and SIX5 genes in a large cohort of patients harboring branchio-oto-renal syndrome calls into question the pathogenic role of SIX5 mutations. | 43 |
| 19851296 | 2010 | Assessment of a polymorphism of SDK1 with hypertension in Japanese Individuals. | 7 |
| 20198315 | 2010 | Association of genetic variants with hemorrhagic stroke in Japanese individuals. | 17 |
| 19851296 | 2010 | Assessment of a polymorphism of SDK1 with hypertension in Japanese Individuals. | 7 |
| 20198315 | 2010 | Association of genetic variants with hemorrhagic stroke in Japanese individuals. | 17 |
| 17357085 | 2007 | Transcription factor SIX5 is mutated in patients with branchio-oto-renal syndrome. | 75 |
Citation
Dessen P
SIX5 (SIX homeobox 5)
Atlas Genet Cytogenet Oncol Haematol. 2016-10-01
Online version: http://atlasgeneticsoncology.org/gene/56442/six5-(six-homeobox-5)
