Identity
HGNC
LOCATION
8q21.3
LOCUSID
ALIAS
CGI-77,DUBA-5,DUBA5,IDDFSDA
FUSION GENES
Non-annotated gene. Preliminary data : if you are an author who wish to write a full paper/card on this gene, contribute in submission tool
Other Information
Locus ID:
NCBI: 51633
MIM: 612021
HGNC: 24281
Ensembl: ENSG00000155100
Variants:
dbSNP: 51633
ClinVar: 51633
TCGA: ENSG00000155100
COSMIC: OTUD6B
RNA/Proteins
Expression (GTEx)
Protein levels (Protein atlas)
References
| Pubmed ID | Year | Title | Citations |
|---|---|---|---|
| 38878112 | 2024 | Otud6b induces pulmonary arterial hypertension by mediating the Calpain-1/HIF-1α signaling pathway. | 0 |
| 38878112 | 2024 | Otud6b induces pulmonary arterial hypertension by mediating the Calpain-1/HIF-1α signaling pathway. | 0 |
| 37634410 | 2023 | MCTS1 enhances the proliferation of laryngeal squamous cell carcinoma via promoting OTUD6B-1 mediated LIN28B deubiquitination. | 0 |
| 37650650 | 2023 | Human OTUD6B positively regulates type I IFN antiviral innate immune responses by deubiquitinating and stabilizing IRF3. | 0 |
| 37634410 | 2023 | MCTS1 enhances the proliferation of laryngeal squamous cell carcinoma via promoting OTUD6B-1 mediated LIN28B deubiquitination. | 0 |
| 37650650 | 2023 | Human OTUD6B positively regulates type I IFN antiviral innate immune responses by deubiquitinating and stabilizing IRF3. | 0 |
| 34354232 | 2022 | OTUD6B-associated intellectual disability: novel variants and genetic exclusion of retinal degeneration as part of a refined phenotype. | 2 |
| 35110537 | 2022 | Deubiquitylase OTUD6B stabilizes the mutated pVHL and suppresses cell migration in clear cell renal cell carcinoma. | 9 |
| 35430327 | 2022 | Novel biallelic variants affecting the OTU domain of the gene OTUD6B associate with severe intellectual disability syndrome and molecular dynamics simulations. | 0 |
| 36059274 | 2022 | The OTUD6B-LIN28B-MYC axis determines the proliferative state in multiple myeloma. | 5 |
| 34354232 | 2022 | OTUD6B-associated intellectual disability: novel variants and genetic exclusion of retinal degeneration as part of a refined phenotype. | 2 |
| 35110537 | 2022 | Deubiquitylase OTUD6B stabilizes the mutated pVHL and suppresses cell migration in clear cell renal cell carcinoma. | 9 |
| 35430327 | 2022 | Novel biallelic variants affecting the OTU domain of the gene OTUD6B associate with severe intellectual disability syndrome and molecular dynamics simulations. | 0 |
| 36059274 | 2022 | The OTUD6B-LIN28B-MYC axis determines the proliferative state in multiple myeloma. | 5 |
| 34680978 | 2021 | Compound Heterozygote of Point Mutation and Chromosomal Microdeletion Involving OTUD6B Coinciding with ZMIZ1 Variant in Syndromic Intellectual Disability. | 6 |
Citation
Dessen P
OTUD6B (OTU deubiquitinase 6B)
Atlas Genet Cytogenet Oncol Haematol. 2016-10-01
Online version: http://atlasgeneticsoncology.org/gene/56448/otud6b-(otu-deubiquitinase-6b)
