Identity
HGNC
LOCATION
1q42.13
LOCUSID
ALIAS
CDG2T,GalNAc-T2
FUSION GENES
Non-annotated gene. Preliminary data : if you are an author who wish to write a full paper/card on this gene, contribute in submission tool
Other Information
Locus ID:
NCBI: 2590
MIM: 602274
HGNC: 4124
Ensembl: ENSG00000143641
Variants:
dbSNP: 2590
ClinVar: 2590
TCGA: ENSG00000143641
COSMIC: GALNT2
RNA/Proteins
| Gene ID | Transcript ID | Uniprot |
|---|---|---|
| ENSG00000143641 | ENST00000366672 | Q10471 |
| ENSG00000143641 | ENST00000366672 | A0A1L7NY50 |
Expression (GTEx)
Pathways
Protein levels (Protein atlas)
PharmGKB
| Entity ID | Name | Type | Evidence | Association | PK | PD | PMIDs |
|---|---|---|---|---|---|---|---|
| PA444552 | Hypertension | Disease | ClinicalAnnotation | associated | PD | ||
| PA448499 | atenolol | Chemical | ClinicalAnnotation | associated | PD |
References
| Pubmed ID | Year | Title | Citations |
|---|---|---|---|
| 36409270 | 2023 | GALNT2 promotes invasiveness of colorectal cancer cells partly through AXL. | 8 |
| 36861373 | 2023 | Leveraging Genetics to Address the Role of GALNT2 on Atherogenic Dyslipidemia. | 0 |
| 37000153 | 2023 | GALNT2 sustains glioma stem cells by promoting CD44 expression. | 3 |
| 37597090 | 2023 | GALNT2, an O-glycosylating enzyme, is a critical regulator of radioresistance of non-small cell lung cancer: evidence from an integrated multi-omics analysis. | 0 |
| 36409270 | 2023 | GALNT2 promotes invasiveness of colorectal cancer cells partly through AXL. | 8 |
| 36861373 | 2023 | Leveraging Genetics to Address the Role of GALNT2 on Atherogenic Dyslipidemia. | 0 |
| 37000153 | 2023 | GALNT2 sustains glioma stem cells by promoting CD44 expression. | 3 |
| 37597090 | 2023 | GALNT2, an O-glycosylating enzyme, is a critical regulator of radioresistance of non-small cell lung cancer: evidence from an integrated multi-omics analysis. | 0 |
| 35055114 | 2022 | Role of GALNT2 on Insulin Sensitivity, Lipid Metabolism and Fat Homeostasis. | 3 |
| 35885984 | 2022 | GALNT2 rs4846914 SNP Is Associated with Obesity, Atherogenic Lipid Traits, and ANGPTL3 Plasma Level. | 0 |
| 36110252 | 2022 | O-Glycosylating Enzyme GALNT2 Predicts Worse Prognosis in Cervical Cancer. | 3 |
| 35055114 | 2022 | Role of GALNT2 on Insulin Sensitivity, Lipid Metabolism and Fat Homeostasis. | 3 |
| 35885984 | 2022 | GALNT2 rs4846914 SNP Is Associated with Obesity, Atherogenic Lipid Traits, and ANGPTL3 Plasma Level. | 0 |
| 36110252 | 2022 | O-Glycosylating Enzyme GALNT2 Predicts Worse Prognosis in Cervical Cancer. | 3 |
| 33171515 | 2021 | GALNT2 Gene Variant rs4846914 Is Associated with Insulin and Insulin Resistance Depending on BMI in PCOS Patients: a Case-Control Study. | 4 |
Citation
Dessen P
GALNT2 (polypeptide N-acetylgalactosaminyltransferase 2)
Atlas Genet Cytogenet Oncol Haematol. 2016-10-01
Online version: http://atlasgeneticsoncology.org/gene/56469/galnt2-(polypeptide-n-acetylgalactosaminyltransferase-2)
