Identity
HGNC
LOCATION
16p11.2
LOCUSID
ALIAS
HAST,HAST3,M-PST,ST1A3,ST1A3/ST1A4,ST1A4,ST1A5,STM,TL-PST
Non-annotated gene. Preliminary data : if you are an author who wish to write a full paper/card on this gene, contribute in submission tool
Other Information
Locus ID:
NCBI: 6818
MIM: 600641
HGNC: 11455
Ensembl: ENSG00000261052
Variants:
dbSNP: 6818
ClinVar: 6818
TCGA: ENSG00000261052
COSMIC: SULT1A3
RNA/Proteins
Expression (GTEx)
Pathways
Protein levels (Protein atlas)
PharmGKB
| Entity ID | Name | Type | Evidence | Association | PK | PD | PMIDs |
|---|---|---|---|---|---|---|---|
| PA166131379 | o-desmethyl-tramadol | Chemical | ClinicalAnnotation, VariantAnnotation | associated | PK | ||
| PA166179720 | tapentadol | Chemical | ClinicalAnnotation, VariantAnnotation | associated | PK | ||
| PA448015 | acetaminophen | Chemical | ClinicalAnnotation, Literature, MultilinkAnnotation, Pathway, VariantAnnotation | associated | PK | 23462933, 26049587 | |
| PA450550 | morphine | Chemical | ClinicalAnnotation, VariantAnnotation | ambiguous | PK | ||
| PA451735 | tramadol | Chemical | ClinicalAnnotation | associated | PK |
References
| Pubmed ID | Year | Title | Citations |
|---|---|---|---|
| 37487659 | 2023 | Farnesoid X receptor represses human sulfotransferase 1A3 expression through direct binding to the promoter. | 0 |
| 38069221 | 2023 | Role of Conformational Dynamics of Sulfotransferases SULT1A1 and SULT1A3 in Substrate Specificity. | 0 |
| 37487659 | 2023 | Farnesoid X receptor represses human sulfotransferase 1A3 expression through direct binding to the promoter. | 0 |
| 38069221 | 2023 | Role of Conformational Dynamics of Sulfotransferases SULT1A1 and SULT1A3 in Substrate Specificity. | 0 |
| 32152050 | 2020 | Interaction of the Brain-Selective Sulfotransferase SULT4A1 with Other Cytosolic Sulfotransferases: Effects on Protein Expression and Function. | 6 |
| 32152050 | 2020 | Interaction of the Brain-Selective Sulfotransferase SULT4A1 with Other Cytosolic Sulfotransferases: Effects on Protein Expression and Function. | 6 |
| 31145702 | 2019 | Impact of SULT1A3/SULT1A4 genetic polymorphisms on the sulfation of phenylephrine and salbutamol by human SULT1A3 allozymes. | 2 |
| 31145702 | 2019 | Impact of SULT1A3/SULT1A4 genetic polymorphisms on the sulfation of phenylephrine and salbutamol by human SULT1A3 allozymes. | 2 |
| 28374858 | 2018 | Sulfotransferase 1A3/4 copy number variation is associated with neurodegenerative disease. | 11 |
| 29705271 | 2018 | Effects of human SULT1A3/SULT1A4 genetic polymorphisms on the sulfation of acetaminophen and opioid drugs by the cytosolic sulfotransferase SULT1A3. | 7 |
| 28374858 | 2018 | Sulfotransferase 1A3/4 copy number variation is associated with neurodegenerative disease. | 11 |
| 29705271 | 2018 | Effects of human SULT1A3/SULT1A4 genetic polymorphisms on the sulfation of acetaminophen and opioid drugs by the cytosolic sulfotransferase SULT1A3. | 7 |
| 28630292 | 2017 | Tetrahydrobiopterin regulates monoamine neurotransmitter sulfonation. | 12 |
| 29025375 | 2017 | Dopamine-induced SULT1A3/4 promotes EMT and cancer stemness in hepatocellular carcinoma. | 14 |
| 28630292 | 2017 | Tetrahydrobiopterin regulates monoamine neurotransmitter sulfonation. | 12 |
Citation
Dessen P
SULT1A3 (sulfotransferase family 1A member 3)
Atlas Genet Cytogenet Oncol Haematol. 2016-10-01
Online version: http://atlasgeneticsoncology.org/gene/56490/gene-explorer/tumors-explorer/
