Non-annotated gene. Preliminary data : if you are an author who wish to write a full paper/card on this gene, contribute in submission tool
Other Information
Locus ID:
NCBI: 56670
MIM: 606381
HGNC: 4542
Ensembl: ENSG00000198829
Variants:
dbSNP: 56670
ClinVar: 56670
TCGA: ENSG00000198829
COSMIC: SUCNR1
RNA/Proteins
| Gene ID | Transcript ID | Uniprot |
|---|---|---|
| ENSG00000198829 | ENST00000362032 | Q9BXA5 |
Expression (GTEx)
Pathways
Protein levels (Protein atlas)
References
| Pubmed ID | Year | Title | Citations |
|---|---|---|---|
| 36652132 | 2023 | Human umbilical cord mesenchymal stem cell-derived exosomes carrying miR-1827 downregulate SUCNR1 to inhibit macrophage M2 polarization and prevent colorectal liver metastasis. | 14 |
| 37315889 | 2023 | Protective effects of the succinate/SUCNR1 axis on damaged hepatocytes in NAFLD. | 3 |
| 36652132 | 2023 | Human umbilical cord mesenchymal stem cell-derived exosomes carrying miR-1827 downregulate SUCNR1 to inhibit macrophage M2 polarization and prevent colorectal liver metastasis. | 14 |
| 37315889 | 2023 | Protective effects of the succinate/SUCNR1 axis on damaged hepatocytes in NAFLD. | 3 |
| 34813893 | 2022 | Succinate receptor 1 inhibits mitochondrial respiration in cancer cells addicted to glutamine. | 9 |
| 34813893 | 2022 | Succinate receptor 1 inhibits mitochondrial respiration in cancer cells addicted to glutamine. | 9 |
| 33127268 | 2021 | Associations of SUCNR1, GRK4, CAMK1D gene polymorphisms and the susceptibility of type 2 diabetes mellitus and essential hypertension in a northern Chinese Han population. | 6 |
| 33776908 | 2021 | Succinate Mediates Tumorigenic Effects via Succinate Receptor 1: Potential for New Targeted Treatment Strategies in Succinate Dehydrogenase Deficient Paragangliomas. | 20 |
| 34133934 | 2021 | Extracellular succinate hyperpolarizes M2 macrophages through SUCNR1/GPR91-mediated Gq signaling. | 43 |
| 34769478 | 2021 | SUCNR1 Is Expressed in Human Placenta and Mediates Angiogenesis: Significance in Gestational Diabetes. | 7 |
| 33127268 | 2021 | Associations of SUCNR1, GRK4, CAMK1D gene polymorphisms and the susceptibility of type 2 diabetes mellitus and essential hypertension in a northern Chinese Han population. | 6 |
| 33776908 | 2021 | Succinate Mediates Tumorigenic Effects via Succinate Receptor 1: Potential for New Targeted Treatment Strategies in Succinate Dehydrogenase Deficient Paragangliomas. | 20 |
| 34133934 | 2021 | Extracellular succinate hyperpolarizes M2 macrophages through SUCNR1/GPR91-mediated Gq signaling. | 43 |
| 34769478 | 2021 | SUCNR1 Is Expressed in Human Placenta and Mediates Angiogenesis: Significance in Gestational Diabetes. | 7 |
| 31735641 | 2020 | Cancer-Derived Succinate Promotes Macrophage Polarization and Cancer Metastasis via Succinate Receptor. | 192 |
Citation
Dessen P
SUCNR1 (succinate receptor 1)
Atlas Genet Cytogenet Oncol Haematol. 2016-10-01
Online version: http://atlasgeneticsoncology.org/gene/56511/sucnr1-(succinate-receptor-1)
