Identity
HGNC
LOCATION
11q23.3
LOCUSID
ALIAS
DFNB111,EVA,EVA1
FUSION GENES
Non-annotated gene. Preliminary data : if you are an author who wish to write a full paper/card on this gene, contribute in submission tool
Other Information
Locus ID:
NCBI: 10205
MIM: 604873
HGNC: 3496
Ensembl: ENSG00000149573
Variants:
dbSNP: 10205
ClinVar: 10205
TCGA: ENSG00000149573
COSMIC: MPZL2
RNA/Proteins
| Gene ID | Transcript ID | Uniprot |
|---|---|---|
| ENSG00000149573 | ENST00000278937 | O60487 |
| ENSG00000149573 | ENST00000278937 | A0A024R3K1 |
| ENSG00000149573 | ENST00000438295 | O60487 |
| ENSG00000149573 | ENST00000438295 | A0A024R3K1 |
Expression (GTEx)
Protein levels (Protein atlas)
References
| Pubmed ID | Year | Title | Citations |
|---|---|---|---|
| 38197511 | 2024 | Recurrent missense variant identified in two unrelated families with MPZL2-related hearing loss, expanding the variant spectrum associated with DFNB111. | 0 |
| 38254107 | 2024 | MPZL2-a common autosomal recessive deafness gene related to moderate sensorineural hearing loss in the Chinese population. | 0 |
| 38197511 | 2024 | Recurrent missense variant identified in two unrelated families with MPZL2-related hearing loss, expanding the variant spectrum associated with DFNB111. | 0 |
| 38254107 | 2024 | MPZL2-a common autosomal recessive deafness gene related to moderate sensorineural hearing loss in the Chinese population. | 0 |
| 37390746 | 2023 | MPZL2 variant analysis with whole exome sequencing in a cohort of Chinese hearing loss patients. | 0 |
| 37390746 | 2023 | MPZL2 variant analysis with whole exome sequencing in a cohort of Chinese hearing loss patients. | 0 |
| 35249471 | 2022 | Upregulation of FHL1, SPNS3, and MPZL2 predicts poor prognosis in pediatric acute myeloid leukemia patients with FLT3-ITD mutation. | 4 |
| 35249471 | 2022 | Upregulation of FHL1, SPNS3, and MPZL2 predicts poor prognosis in pediatric acute myeloid leukemia patients with FLT3-ITD mutation. | 4 |
| 33234333 | 2021 | A homozygous MPZL2 deletion is associated with non syndromic hearing loss in a moroccan family. | 3 |
| 33234333 | 2021 | A homozygous MPZL2 deletion is associated with non syndromic hearing loss in a moroccan family. | 3 |
| 31997489 | 2020 | Epithelial V-like antigen 1 promotes hepatocellular carcinoma growth and metastasis via the ERBB-PI3K-AKT pathway. | 10 |
| 31997489 | 2020 | Epithelial V-like antigen 1 promotes hepatocellular carcinoma growth and metastasis via the ERBB-PI3K-AKT pathway. | 10 |
| 29982980 | 2018 | MPZL2 is a novel gene associated with autosomal recessive nonsyndromic moderate hearing loss. | 11 |
| 29982980 | 2018 | MPZL2 is a novel gene associated with autosomal recessive nonsyndromic moderate hearing loss. | 11 |
| 26677976 | 2016 | Eva1 Maintains the Stem-like Character of Glioblastoma-Initiating Cells by Activating the Noncanonical NF-κB Signaling Pathway. | 24 |
Citation
Dessen P
MPZL2 (myelin protein zero like 2)
Atlas Genet Cytogenet Oncol Haematol. 2016-10-01
Online version: http://atlasgeneticsoncology.org/gene/56516/mpzl2-(myelin-protein-zero-like-2)
