Non-annotated gene. Preliminary data : if you are an author who wish to write a full paper/card on this gene, contribute in submission tool
Other Information
Locus ID:
NCBI: 866
MIM: 122500
HGNC: 1540
Ensembl: ENSG00000170099
Variants:
dbSNP: 866
ClinVar: 866
TCGA: ENSG00000170099
COSMIC: SERPINA6
RNA/Proteins
| Gene ID | Transcript ID | Uniprot |
|---|---|---|
| ENSG00000170099 | ENST00000341584 | P08185 |
| ENSG00000170099 | ENST00000555056 | G3V350 |
| ENSG00000170099 | ENST00000557225 | G3V4V7 |
Expression (GTEx)
Protein levels (Protein atlas)
References
| Pubmed ID | Year | Title | Citations |
|---|---|---|---|
| 38042488 | 2024 | Position-specific N- and O-glycosylation of the reactive center loop impacts neutrophil elastase-mediated proteolysis of corticosteroid-binding globulin. | 1 |
| 38042488 | 2024 | Position-specific N- and O-glycosylation of the reactive center loop impacts neutrophil elastase-mediated proteolysis of corticosteroid-binding globulin. | 1 |
| 37745713 | 2023 | Plasma cortisol-linked gene networks in hepatic and adipose tissues implicate corticosteroid-binding globulin in modulating tissue glucocorticoid action and cardiovascular risk. | 1 |
| 37745713 | 2023 | Plasma cortisol-linked gene networks in hepatic and adipose tissues implicate corticosteroid-binding globulin in modulating tissue glucocorticoid action and cardiovascular risk. | 1 |
| 35217314 | 2022 | Stress-related genetic components in attention-deficit/hyperactivity disorder (ADHD): Effects of the SERPINA6 and SERPINA1 genetic markers in a family-based brazilian sample. | 1 |
| 35217314 | 2022 | Stress-related genetic components in attention-deficit/hyperactivity disorder (ADHD): Effects of the SERPINA6 and SERPINA1 genetic markers in a family-based brazilian sample. | 1 |
| 33469137 | 2021 | Variation in the SERPINA6/SERPINA1 locus alters morning plasma cortisol, hepatic corticosteroid binding globulin expression, gene expression in peripheral tissues, and risk of cardiovascular disease. | 24 |
| 33469137 | 2021 | Variation in the SERPINA6/SERPINA1 locus alters morning plasma cortisol, hepatic corticosteroid binding globulin expression, gene expression in peripheral tissues, and risk of cardiovascular disease. | 24 |
| 33085168 | 2020 | Pyrexia and acidosis act independently of neutrophil elastase reactive center loop cleavage to effect cortisol release from corticosteroid-binding globulin. | 5 |
| 33085168 | 2020 | Pyrexia and acidosis act independently of neutrophil elastase reactive center loop cleavage to effect cortisol release from corticosteroid-binding globulin. | 5 |
| 30160799 | 2019 | Total and high-affinity corticosteroid-binding globulin depletion in septic shock is associated with mortality. | 6 |
| 30452386 | 2019 | Neutrophil elastase-cleaved corticosteroid-binding globulin is absent in human plasma. | 3 |
| 31103428 | 2019 | NewBG: A surrogate corticosteroid-binding globulin with an unprecedentedly high ligand release efficacy. | 1 |
| 30160799 | 2019 | Total and high-affinity corticosteroid-binding globulin depletion in septic shock is associated with mortality. | 6 |
| 30452386 | 2019 | Neutrophil elastase-cleaved corticosteroid-binding globulin is absent in human plasma. | 3 |
Citation
Dessen P
SERPINA6 (serpin family A member 6)
Atlas Genet Cytogenet Oncol Haematol. 2016-10-01
Online version: http://atlasgeneticsoncology.org/gene/56521/serpina6-(serpin-family-a-member-6)
