Identity
HGNC
LOCATION
7p14.1
LOCUSID
ALIAS
HVPS41,HVSP41,hVps41p
FUSION GENES
Non-annotated gene. Preliminary data : if you are an author who wish to write a full paper/card on this gene, contribute in submission tool
Other Information
Locus ID:
NCBI: 27072
MIM: 605485
HGNC: 12713
Ensembl: ENSG00000006715
Variants:
dbSNP: 27072
ClinVar: 27072
TCGA: ENSG00000006715
COSMIC: VPS41
RNA/Proteins
Expression (GTEx)
Protein levels (Protein atlas)
References
| Pubmed ID | Year | Title | Citations |
|---|---|---|---|
| 33764426 | 2021 | Bi-allelic variants in HOPS complex subunit VPS41 cause cerebellar ataxia and abnormal membrane trafficking. | 22 |
| 33851776 | 2021 | Neurodegenerative VPS41 variants inhibit HOPS function and mTORC1-dependent TFEB/TFE3 regulation. | 18 |
| 33764426 | 2021 | Bi-allelic variants in HOPS complex subunit VPS41 cause cerebellar ataxia and abnormal membrane trafficking. | 22 |
| 33851776 | 2021 | Neurodegenerative VPS41 variants inhibit HOPS function and mTORC1-dependent TFEB/TFE3 regulation. | 18 |
| 32808683 | 2020 | Loss-of-Function Variants in HOPS Complex Genes VPS16 and VPS41 Cause Early Onset Dystonia Associated with Lysosomal Abnormalities. | 39 |
| 32808683 | 2020 | Loss-of-Function Variants in HOPS Complex Genes VPS16 and VPS41 Cause Early Onset Dystonia Associated with Lysosomal Abnormalities. | 39 |
| 31194677 | 2019 | Vps8 overexpression inhibits HOPS-dependent trafficking routes by outcompeting Vps41/Lt. | 13 |
| 31194677 | 2019 | Vps8 overexpression inhibits HOPS-dependent trafficking routes by outcompeting Vps41/Lt. | 13 |
| 30508205 | 2018 | Distinct functional roles of Vps41-mediated neuroprotection in Alzheimer's and Parkinson's disease models of neurodegeneration. | 22 |
| 30508205 | 2018 | Distinct functional roles of Vps41-mediated neuroprotection in Alzheimer's and Parkinson's disease models of neurodegeneration. | 22 |
| 28931724 | 2017 | VPS18 recruits VPS41 to the human HOPS complex via a RING-RING interaction. | 12 |
| 28931724 | 2017 | VPS18 recruits VPS41 to the human HOPS complex via a RING-RING interaction. | 12 |
| 25445562 | 2014 | RILP interacts with HOPS complex via VPS41 subunit to regulate endocytic trafficking. | 33 |
| 25445562 | 2014 | RILP interacts with HOPS complex via VPS41 subunit to regulate endocytic trafficking. | 33 |
| 23167963 | 2013 | The HOPS proteins hVps41 and hVps39 are required for homotypic and heterotypic late endosome fusion. | 57 |
Citation
Dessen P
VPS41 (VPS41 subunit of HOPS complex)
Atlas Genet Cytogenet Oncol Haematol. 2016-10-01
Online version: http://atlasgeneticsoncology.org/gene/56533/vps41-(vps41-subunit-of-hops-complex)
