Non-annotated gene. Preliminary data : if you are an author who wish to write a full paper/card on this gene, contribute in submission tool
Other Information
Locus ID:
NCBI: 23353
MIM: 607723
HGNC: 18587
Ensembl: ENSG00000164828
Variants:
dbSNP: 23353
ClinVar: 23353
TCGA: ENSG00000164828
COSMIC: SUN1
RNA/Proteins
Expression (GTEx)
Pathways
| Pathway | Source | External ID |
|---|---|---|
| Cell Cycle | REACTOME | R-HSA-1640170 |
| Meiosis | REACTOME | R-HSA-1500620 |
| Meiotic synapsis | REACTOME | R-HSA-1221632 |
Protein levels (Protein atlas)
References
| Pubmed ID | Year | Title | Citations |
|---|---|---|---|
| 37639327 | 2024 | SUN1 facilitates CHMP7 nuclear influx and injury cascades in sporadic amyotrophic lateral sclerosis. | 5 |
| 37639327 | 2024 | SUN1 facilitates CHMP7 nuclear influx and injury cascades in sporadic amyotrophic lateral sclerosis. | 5 |
| 36933034 | 2023 | Loss of SUN1 function in spermatocytes disrupts the attachment of telomeres to the nuclear envelope and contributes to non-obstructive azoospermia in humans. | 2 |
| 36933034 | 2023 | Loss of SUN1 function in spermatocytes disrupts the attachment of telomeres to the nuclear envelope and contributes to non-obstructive azoospermia in humans. | 2 |
| 35587281 | 2022 | Homozygous missense mutation in CCDC155 disrupts the transmembrane distribution of CCDC155 and SUN1, resulting in non-obstructive azoospermia and premature ovarian insufficiency in humans. | 5 |
| 35587281 | 2022 | Homozygous missense mutation in CCDC155 disrupts the transmembrane distribution of CCDC155 and SUN1, resulting in non-obstructive azoospermia and premature ovarian insufficiency in humans. | 5 |
| 33686165 | 2021 | The SUN2-nesprin-2 LINC complex and KIF20A function in the Golgi dispersal. | 9 |
| 34039995 | 2021 | The SUN1-SPDYA interaction plays an essential role in meiosis prophase I. | 10 |
| 34580332 | 2021 | Nuclear restriction of HIV-1 infection by SUN1. | 1 |
| 33686165 | 2021 | The SUN2-nesprin-2 LINC complex and KIF20A function in the Golgi dispersal. | 9 |
| 34039995 | 2021 | The SUN1-SPDYA interaction plays an essential role in meiosis prophase I. | 10 |
| 34580332 | 2021 | Nuclear restriction of HIV-1 infection by SUN1. | 1 |
| 31935926 | 2020 | SUN1/2 Are Essential for RhoA/ROCK-Regulated Actomyosin Activity in Isolated Vascular Smooth Muscle Cells. | 15 |
| 32931086 | 2020 | The SUN1 splicing variants SUN1_888 and SUN1_916 differentially regulate nucleolar structure. | 2 |
| 31935926 | 2020 | SUN1/2 Are Essential for RhoA/ROCK-Regulated Actomyosin Activity in Isolated Vascular Smooth Muscle Cells. | 15 |
Citation
Dessen P
SUN1 (Sad1 and UNC84 domain containing 1)
Atlas Genet Cytogenet Oncol Haematol. 2016-10-01
Online version: http://atlasgeneticsoncology.org/gene/56534/sun1-(sad1-and-unc84-domain-containing-1)
