GOLGA1 (golgin A1)

2016-10-01  

Identity

HGNC
GOLGA1
LOCATION
9q33.3
LOCUSID
2800
ALIAS
golgin-97
FUSION GENES
Show Gene Fusions

Other Information

Locus ID:

NCBI: 2800
MIM: 602502
HGNC: 4424
Ensembl: ENSG00000136935

Variants:

dbSNP: 2800
ClinVar: 2800
TCGA: ENSG00000136935
COSMIC: GOLGA1

RNA/Proteins

Gene IDTranscript IDUniprot
ENSG00000136935ENST00000373555Q92805
ENSG00000136935ENST00000421514Q5T165
ENSG00000136935ENST00000475407R4GNH1
ENSG00000136935ENST00000485337H0YE54

Expression (GTEx)

0
5
10
15
20
25
30
35
40
Adipose - Subcutaneous
Adipose - Visceral
Adrenal Gland
Artery - Aorta
Artery - Tibial
Bladder
Brain - Amygdala
Brain - Anterior cingulate cortex
Brain - Caudate
Brain - Cerebellar Hemisphere
Brain - Cerebellum
Brain - Cortex
Brain - Frontal Cortex
Brain - Hippocampus
Brain - Hypothalamus
Brain - Nucleus accumbens
Brain - Putamen
Brain - Spinal cord
Brain - Substantia nigra
Breast - Mammary Tissue
Cells - Cultured fibroblasts
Cells - EBV - transformed lymphocytes
Cervix - Ectocervix
Cervix - Endocervix
Colon - Sigmoid
Colon - Transverse
Esophagus - Gastroesophageal Junction
Esophagus - Mucosa
Esophagus - Muscularis
Fallopian Tube
Heart - Atrial Appendage
Heart - Left Ventricle
Kidney - Cortex
Kidney - Medulla
Liver
Lung
Minor Salivary Gland
Muscle - Skeletal
Nerve - Tibial
Ovary
Pancreas
Pituitary
Prostate
Skin - Not Sun Exposed
Skin - Sun Exposed
Small Intestine - Terminal Ileum
Spleen
Stomach
Testis
Thyroid
Uterus
Vagina
Whole Blood

Pathways

PathwaySourceExternal ID
Vesicle-mediated transportREACTOMER-HSA-5653656
Membrane TraffickingREACTOMER-HSA-199991
Intra-Golgi and retrograde Golgi-to-ER trafficREACTOMER-HSA-6811442
Retrograde transport at the Trans-Golgi-NetworkREACTOMER-HSA-6811440

Protein levels (Protein atlas)

Not detected
Low
Medium
High
cerebral cortex
cerebellum
hippocampus
caudate
thyroid gland
parathyroid gland
adrenal gland
nasopharynx
bronchus
lung
oral mucosa
salivary gland
esophagus
stomach 1
stomach 2
duodenum
small intestine
colon
rectum
liver
gallbladder
pancreas
kidney
urinary bladder
testis
epididymis
seminal vesicle
prostate
vagina
ovary
fallopian tube
endometrium 1
endometrium 2
cervix, uterine
placenta
breast
heart muscle
smooth muscle
skeletal muscle
soft tissue 1
soft tissue 2
adipose tissue
skin 1
skin 2
appendix
spleen
lymph node
tonsil
bone marrow

References

Pubmed IDYearTitleCitations
349698532022PKD-dependent PARP12-catalyzed mono-ADP-ribosylation of Golgin-97 is required for E-cadherin transport from Golgi to plasma membrane.15
349698532022PKD-dependent PARP12-catalyzed mono-ADP-ribosylation of Golgin-97 is required for E-cadherin transport from Golgi to plasma membrane.15
332396402020Spatial proteomics defines the content of trafficking vesicles captured by golgin tethers.35
332396402020Spatial proteomics defines the content of trafficking vesicles captured by golgin tethers.35
203796142010Personalized smoking cessation: interactions between nicotine dose, dependence and quit-success genotype score.78
205831702010Follow-up association studies of chromosome region 9q and nonsyndromic cleft lip/palate.13
206106572010FIP1/RCP binding to Golgin-97 regulates retrograde transport from recycling endosomes to the trans-Golgi network.23
203796142010Personalized smoking cessation: interactions between nicotine dose, dependence and quit-success genotype score.78
205831702010Follow-up association studies of chromosome region 9q and nonsyndromic cleft lip/palate.13
206106572010FIP1/RCP binding to Golgin-97 regulates retrograde transport from recycling endosomes to the trans-Golgi network.23
172764772007A host cell membrane protein, golgin-97, is essential for poxvirus morphogenesis.8
172764772007A host cell membrane protein, golgin-97, is essential for poxvirus morphogenesis.8
156547692005The trans-Golgi network GRIP-domain proteins form alpha-helical homodimers.13
162627252005E-cadherin transport from the trans-Golgi network in tubulovesicular carriers is selectively regulated by golgin-97.44
156547692005The trans-Golgi network GRIP-domain proteins form alpha-helical homodimers.13

Citation

Dessen P

GOLGA1 (golgin A1)

Atlas Genet Cytogenet Oncol Haematol. 2016-10-01

Online version: http://atlasgeneticsoncology.org/gene/56536/golga1-(golgin-a1)