CDCA7L (cell division cycle associated 7 like)

2016-10-01  

Identity

HGNC
LOCATION
7p15.3
LOCUSID
ALIAS
JPO2,R1,RAM2
FUSION GENES

Other Information

Locus ID:

NCBI: 55536
MIM: 609685
HGNC: 30777
Ensembl: ENSG00000164649

Variants:

dbSNP: 55536
ClinVar: 55536
TCGA: ENSG00000164649
COSMIC: CDCA7L

RNA/Proteins

Gene IDTranscript IDUniprot
ENSG00000164649ENST00000356195Q96GN5
ENSG00000164649ENST00000373934Q96GN5
ENSG00000164649ENST00000406877Q96GN5
ENSG00000164649ENST00000406877A0A024RA51
ENSG00000164649ENST00000435031C9JFL7
ENSG00000164649ENST00000435717H7C1J6
ENSG00000164649ENST00000447180C9J8L0
ENSG00000164649ENST00000457951C9IZR6

Expression (GTEx)

0
5
10
15
20
25
30
35
40

Protein levels (Protein atlas)

Not detected
Low
Medium
High

References

Pubmed IDYearTitleCitations
303893172019Cell division cycle associated 7 like predicts unfavorable prognosis and promotes invasion in glioma.2
306203902019Distinct genome-wide methylation patterns in sporadic and hereditary nonfunctioning pancreatic neuroendocrine tumors.20
311732172019CDCA7L promotes glioma proliferation by targeting CCND1 and predicts an unfavorable prognosis.8
303893172019Cell division cycle associated 7 like predicts unfavorable prognosis and promotes invasion in glioma.2
306203902019Distinct genome-wide methylation patterns in sporadic and hereditary nonfunctioning pancreatic neuroendocrine tumors.20
311732172019CDCA7L promotes glioma proliferation by targeting CCND1 and predicts an unfavorable prognosis.8
300421752018R1 Regulates Prostate Tumor Growth and Progression By Transcriptional Suppression of the E3 Ligase HUWE1 to Stabilize c-Myc.4
300421752018R1 Regulates Prostate Tumor Growth and Progression By Transcriptional Suppression of the E3 Ligase HUWE1 to Stabilize c-Myc.4
270131962016JPO2/CDCA7L and LEDGF/p75 Are Novel Mediators of PI3K/AKT Signaling and Aggressive Phenotypes in Medulloblastoma.10
278829332016Multiple myeloma risk variant at 7p15.3 creates an IRF4-binding site and interferes with CDCA7L expression.17
270131962016JPO2/CDCA7L and LEDGF/p75 Are Novel Mediators of PI3K/AKT Signaling and Aggressive Phenotypes in Medulloblastoma.10
278829332016Multiple myeloma risk variant at 7p15.3 creates an IRF4-binding site and interferes with CDCA7L expression.17
254804952015The 7p15.3 (rs4487645) association for multiple myeloma shows strong allele-specific regulation of the MYC-interacting gene CDCA7L in malignant plasma cells.19
262459782015Multiple cellular proteins interact with LEDGF/p75 through a conserved unstructured consensus motif.35
254804952015The 7p15.3 (rs4487645) association for multiple myeloma shows strong allele-specific regulation of the MYC-interacting gene CDCA7L in malignant plasma cells.19

Citation

Dessen P

CDCA7L (cell division cycle associated 7 like)

Atlas Genet Cytogenet Oncol Haematol. 2016-10-01

Online version: http://atlasgeneticsoncology.org/gene/56537/cdca7l-(cell-division-cycle-associated-7-like)