Non-annotated gene. Preliminary data : if you are an author who wish to write a full paper/card on this gene, contribute in submission tool
Other Information
Locus ID:
NCBI: 1130
MIM: 606897
HGNC: 1968
Ensembl: ENSG00000143669
Variants:
dbSNP: 1130
ClinVar: 1130
TCGA: ENSG00000143669
COSMIC: LYST
RNA/Proteins
| Gene ID | Transcript ID | Uniprot |
|---|---|---|
| ENSG00000143669 | ENST00000389793 | Q99698 |
| ENSG00000143669 | ENST00000389794 | A0A0A0MRZ6 |
| ENSG00000143669 | ENST00000487530 | H7C4F5 |
Expression (GTEx)
References
| Pubmed ID | Year | Title | Citations |
|---|---|---|---|
| 37788905 | 2024 | Spectrum of LYST mutations in Chediak-Higashi syndrome: a report of novel variants and a comprehensive review of the literature. | 1 |
| 37788905 | 2024 | Spectrum of LYST mutations in Chediak-Higashi syndrome: a report of novel variants and a comprehensive review of the literature. | 1 |
| 36707427 | 2023 | LYST deficiency impairs autophagic lysosome reformation in neurons and alters lysosome number and size. | 6 |
| 38282619 | 2023 | Lysosomal trafficking regulator restricts intracellular growth of Coxiella burnetii by inhibiting the expansion of Coxiella-containing vacuole and upregulating nos2 expression. | 0 |
| 36707427 | 2023 | LYST deficiency impairs autophagic lysosome reformation in neurons and alters lysosome number and size. | 6 |
| 38282619 | 2023 | Lysosomal trafficking regulator restricts intracellular growth of Coxiella burnetii by inhibiting the expansion of Coxiella-containing vacuole and upregulating nos2 expression. | 0 |
| 34483340 | 2022 | Chédiak-Higashi syndrome presenting as a hereditary spastic paraplegia. | 1 |
| 34483340 | 2022 | Chédiak-Higashi syndrome presenting as a hereditary spastic paraplegia. | 1 |
| 31906877 | 2020 | Identification of a compound heterozygote in LYST gene: a case report on Chediak-Higashi syndrome. | 3 |
| 31906877 | 2020 | Identification of a compound heterozygote in LYST gene: a case report on Chediak-Higashi syndrome. | 3 |
| 31795567 | 2019 | [A novel mutation of the LYST gene in a Chinese family with Chediak-Higashi syndrome]. | 0 |
| 31795567 | 2019 | [A novel mutation of the LYST gene in a Chinese family with Chediak-Higashi syndrome]. | 0 |
| 29652989 | 2018 | [Analysis of clinical characteristics and genetic mutation in a pedigree affected with Chediak-Higashi syndrome]. | 0 |
| 29652989 | 2018 | [Analysis of clinical characteristics and genetic mutation in a pedigree affected with Chediak-Higashi syndrome]. | 0 |
| 27781387 | 2017 | Clinical presentation and outcome of pediatric patients with hemophagocytic lymphohistiocytosis in China: A retrospective multicenter study. | 29 |
Citation
Dessen P
LYST (lysosomal trafficking regulator)
Atlas Genet Cytogenet Oncol Haematol. 2016-10-01
Online version: http://atlasgeneticsoncology.org/gene/56541/lyst-(lysosomal-trafficking-regulator)
