TFAP2D (transcription factor AP-2 delta)

2016-10-01  

Identity

HGNC
LOCATION
6p12.3
LOCUSID
ALIAS
AP-2delta,TFAP2BL1

Other Information

Locus ID:

NCBI: 83741
MIM: 610161
HGNC: 15581
Ensembl: ENSG00000008197

Variants:

dbSNP: 83741
ClinVar: 83741
TCGA: ENSG00000008197
COSMIC: TFAP2D

RNA/Proteins

Gene IDTranscript IDUniprot
ENSG00000008197ENST00000008391Q7Z6R9

Expression (GTEx)

0
1

Pathways

PathwaySourceExternal ID
Gene ExpressionREACTOMER-HSA-74160
Generic Transcription PathwayREACTOMER-HSA-212436
Transcriptional regulation by the AP-2 (TFAP2) family of transcription factorsREACTOMER-HSA-8864260
Activation of the TFAP2 (AP-2) family of transcription factorsREACTOMER-HSA-8866907
Negative regulation of activity of TFAP2 (AP-2) family transcription factorsREACTOMER-HSA-8866904

References

Pubmed IDYearTitleCitations
365528872022AP-2δ Is the Most Relevant Target of AP-2 Family-Focused Cancer Therapy and Affects Genome Organization.2
365528872022AP-2δ Is the Most Relevant Target of AP-2 Family-Focused Cancer Therapy and Affects Genome Organization.2
321435732020Upregulation of the transcription factor TFAP2D is associated with aggressive tumor phenotype in prostate cancer lacking the TMPRSS2:ERG fusion.7
321435732020Upregulation of the transcription factor TFAP2D is associated with aggressive tumor phenotype in prostate cancer lacking the TMPRSS2:ERG fusion.7
309751992019A human specific Alu DNA cassette is found flanking the genes of transcription factor AP2.2
309751992019A human specific Alu DNA cassette is found flanking the genes of transcription factor AP2.2
247895762014Regulation of the HMOX1 gene by the transcription factor AP-2δ with unique DNA binding site.4
247895762014Regulation of the HMOX1 gene by the transcription factor AP-2δ with unique DNA binding site.4
166845052006Regulation of integrin alpha10 expression in chondrocytes by the transcription factors AP-2epsilon and Ets-1.11
166845052006Regulation of integrin alpha10 expression in chondrocytes by the transcription factors AP-2epsilon and Ets-1.11
117331872002Cloning and characterization of a novel human transcription factor AP-2 beta like gene (TFAP2BL1).10
117331872002Cloning and characterization of a novel human transcription factor AP-2 beta like gene (TFAP2BL1).10

Citation

Dessen P

TFAP2D (transcription factor AP-2 delta)

Atlas Genet Cytogenet Oncol Haematol. 2016-10-01

Online version: http://atlasgeneticsoncology.org/gene/56546/tfap2d-(transcription-factor-ap-2-delta)