ANGPTL8 (angiopoietin like 8)

2016-10-01  

Identity

HGNC
LOCATION
19p13.2
LOCUSID
ALIAS
C19orf80,PRO1185,PVPA599,RIFL,TD26

Other Information

Locus ID:

NCBI: 55908
MIM: 616223
HGNC: 24933
Ensembl: ENSG00000130173

Variants:

dbSNP: 55908
ClinVar: 55908
TCGA: ENSG00000130173
COSMIC: ANGPTL8

RNA/Proteins

Gene IDTranscript IDUniprot
ENSG00000130173ENST00000252453Q6UXH0
ENSG00000130173ENST00000587543K7EJY6
ENSG00000130173ENST00000591200K7EIY2
ENSG00000130173ENST00000616433Q6UXH0

Expression (GTEx)

0
50
100
150

Pathways

PathwaySourceExternal ID
MetabolismREACTOMER-HSA-1430728
Metabolism of lipids and lipoproteinsREACTOMER-HSA-556833
Lipid digestion, mobilization, and transportREACTOMER-HSA-73923
Lipoprotein metabolismREACTOMER-HSA-174824
Chylomicron-mediated lipid transportREACTOMER-HSA-174800

References

Pubmed IDYearTitleCitations
379629082024Angiopoietin-like protein 8: a multifaceted protein instrumental in regulating triglyceride metabolism.1
388438642024The correlations between angiopoietin like 8 and cardiometabolic risk factors in Saudi women with type 2 diabetes mellitus: A pilot study.0
379629082024Angiopoietin-like protein 8: a multifaceted protein instrumental in regulating triglyceride metabolism.1
388438642024The correlations between angiopoietin like 8 and cardiometabolic risk factors in Saudi women with type 2 diabetes mellitus: A pilot study.0
365295242023ANGPTL8 links inflammation and poor differentiation, which are characteristics of malignant renal cell carcinoma.5
367635332023Angiopoietin-like protein 4/8 complex-mediated plasmin generation leads to cleavage of the complex and restoration of LPL activity.8
367688092023The ANGPTL3-4-8 Axis in Normal Gestation and in Gestational Diabetes, and Its Potential Involvement in Fetal Growth.2
368253972023Betatrophin, elabela, asprosin, glucagon and subfatin peptides in breast tissue, blood and milk in gestational diabetes.0
372598622023Plasma ANGPTL8 Levels and Risk for Secondary Cardiovascular Events in Japanese Patients With Stable Coronary Artery Disease Receiving Statin Therapy.0
374816702023LILRB2/PirB mediates macrophage recruitment in fibrogenesis of nonalcoholic steatohepatitis.3
376797502023Genetic predisposition to nonalcoholic fatty liver disease: insights from ANGPTL8 gene variants in Iranian adults.0
377625442023Increased Levels of Circulating IGFBP4 and ANGPTL8 with a Prospective Role in Diabetic Nephropathy.2
379476412023The Proinflammatory Role of ANGPTL8 R59W Variant in Modulating Inflammation through NF-κB Signaling Pathway under TNFα Stimulation.0
365295242023ANGPTL8 links inflammation and poor differentiation, which are characteristics of malignant renal cell carcinoma.5
367635332023Angiopoietin-like protein 4/8 complex-mediated plasmin generation leads to cleavage of the complex and restoration of LPL activity.8

Citation

Dessen P

ANGPTL8 (angiopoietin like 8)

Atlas Genet Cytogenet Oncol Haematol. 2016-10-01

Online version: http://atlasgeneticsoncology.org/gene/56550/angptl8-(angiopoietin-like-8)