Non-annotated gene. Preliminary data : if you are an author who wish to write a full paper/card on this gene, contribute in submission tool
Other Information
Locus ID:
NCBI: 10661
MIM: 600599
HGNC: 6345
Ensembl: ENSG00000105610
Variants:
dbSNP: 10661
ClinVar: 10661
TCGA: ENSG00000105610
COSMIC: KLF1
RNA/Proteins
| Gene ID | Transcript ID | Uniprot |
|---|---|---|
| ENSG00000105610 | ENST00000264834 | Q13351 |
Expression (GTEx)
Protein levels (Protein atlas)
References
| Pubmed ID | Year | Title | Citations |
|---|---|---|---|
| 38429690 | 2024 | Targeted next-generation sequencing and long-read HiFi sequencing provide novel insights into clinically significant KLF1 variants. | 0 |
| 38429690 | 2024 | Targeted next-generation sequencing and long-read HiFi sequencing provide novel insights into clinically significant KLF1 variants. | 0 |
| 36939018 | 2023 | Whole exome sequencing and rare variant association study to identify genetic modifiers, KLF1 mutations, and a novel double mutation in Thai patients with hemoglobin E/beta-thalassemia. | 0 |
| 37165057 | 2023 | Identification of a genomic DNA sequence that quantitatively modulates KLF1 transcription factor expression in differentiating human hematopoietic cells. | 1 |
| 37307706 | 2023 | VPS37C facilitates erythroid differentiation by promoting EKLF stability. | 0 |
| 36939018 | 2023 | Whole exome sequencing and rare variant association study to identify genetic modifiers, KLF1 mutations, and a novel double mutation in Thai patients with hemoglobin E/beta-thalassemia. | 0 |
| 37165057 | 2023 | Identification of a genomic DNA sequence that quantitatively modulates KLF1 transcription factor expression in differentiating human hematopoietic cells. | 1 |
| 37307706 | 2023 | VPS37C facilitates erythroid differentiation by promoting EKLF stability. | 0 |
| 35013432 | 2022 | Epigenomic analysis of KLF1 haploinsufficiency in primary human erythroblasts. | 7 |
| 35013432 | 2022 | Epigenomic analysis of KLF1 haploinsufficiency in primary human erythroblasts. | 7 |
| 33388857 | 2021 | Krüppel-like factor 1 (KLF1) gene single nucleotide polymorphisms in sickle cell disease and its association with disease-related morbidities. | 6 |
| 34227100 | 2021 | Severe neonatal haemolytic anaemia caused by compound heterozygous KLF1 mutations: report of four families and literature review. | 5 |
| 34304709 | 2021 | Krüppel-like factor 1 (KLF1) promoted the proliferation, migration and invasion of human lens epithelial cells by enhancing the expression of Zinc Finger and BTB Domain Containing 7A (ZBTB7A) and activating Wnt/β-catenin pathway. | 8 |
| 34535703 | 2021 | Novel variants in Krueppel like factor 1 that cause persistence of fetal hemoglobin in In(Lu) individuals. | 4 |
| 34554218 | 2021 | Two brothers with a novel KLF1 mutation. | 0 |
Citation
Dessen P
KLF1 (Kruppel like factor 1)
Atlas Genet Cytogenet Oncol Haematol. 2016-10-01
Online version: http://atlasgeneticsoncology.org/gene/56559/klf1-(kruppel-like-factor-1)
