Identity
HGNC
LOCATION
Xq12
LOCUSID
ALIAS
Las1,Las1-like,WTS,dJ475B7.2
FUSION GENES
Non-annotated gene. Preliminary data : if you are an author who wish to write a full paper/card on this gene, contribute in submission tool
Other Information
Locus ID:
NCBI: 81887
MIM: 300964
HGNC: 25726
Ensembl: ENSG00000001497
Variants:
dbSNP: 81887
ClinVar: 81887
TCGA: ENSG00000001497
COSMIC: LAS1L
RNA/Proteins
Expression (GTEx)
Pathways
Protein levels (Protein atlas)
References
| Pubmed ID | Year | Title | Citations |
|---|---|---|---|
| 33664239 | 2021 | Inhibiting β-catenin disables nucleolar functions in triple-negative breast cancer. | 11 |
| 33664239 | 2021 | Inhibiting β-catenin disables nucleolar functions in triple-negative breast cancer. | 11 |
| 22083961 | 2012 | The evolutionarily conserved protein Las1 is required for pre-rRNA processing at both ends of ITS2. | 48 |
| 22190735 | 2012 | LAS1L interacts with the mammalian Rix1 complex to regulate ribosome biogenesis. | 63 |
| 22872859 | 2012 | Five friends of methylated chromatin target of protein-arginine-methyltransferase[prmt]-1 (chtop), a complex linking arginine methylation to desumoylation. | 37 |
| 22083961 | 2012 | The evolutionarily conserved protein Las1 is required for pre-rRNA processing at both ends of ITS2. | 48 |
| 22190735 | 2012 | LAS1L interacts with the mammalian Rix1 complex to regulate ribosome biogenesis. | 63 |
| 22872859 | 2012 | Five friends of methylated chromatin target of protein-arginine-methyltransferase[prmt]-1 (chtop), a complex linking arginine methylation to desumoylation. | 37 |
| 20647540 | 2010 | Las1L is a nucleolar protein required for cell proliferation and ribosome biogenesis. | 39 |
| 20647540 | 2010 | Las1L is a nucleolar protein required for cell proliferation and ribosome biogenesis. | 39 |
Citation
Dessen P
LAS1L (LAS1 like ribosome biogenesis factor)
Atlas Genet Cytogenet Oncol Haematol. 2016-10-01
Online version: http://atlasgeneticsoncology.org/gene/56577/las1l-(las1-like-ribosome-biogenesis-factor)
