Non-annotated gene. Preliminary data : if you are an author who wish to write a full paper/card on this gene, contribute in submission tool
Other Information
Locus ID:
NCBI: 1810
MIM: 601482
HGNC: 3017
Ensembl: ENSG00000117505
Variants:
dbSNP: 1810
ClinVar: 1810
TCGA: ENSG00000117505
COSMIC: DR1
RNA/Proteins
| Gene ID | Transcript ID | Uniprot |
|---|---|---|
| ENSG00000117505 | ENST00000370267 | Q01658 |
| ENSG00000117505 | ENST00000370267 | Q658N3 |
| ENSG00000117505 | ENST00000370272 | Q01658 |
| ENSG00000117505 | ENST00000370272 | Q658N3 |
Expression (GTEx)
Pathways
| Pathway | Source | External ID |
|---|---|---|
| Chromatin organization | REACTOME | R-HSA-4839726 |
| Chromatin modifying enzymes | REACTOME | R-HSA-3247509 |
| HATs acetylate histones | REACTOME | R-HSA-3214847 |
Protein levels (Protein atlas)
References
| Pubmed ID | Year | Title | Citations |
|---|---|---|---|
| 38194758 | 2024 | Downregulation of transcription 1 hinders the replication of Dabie bandavirus by promoting the expression of TLR7, TLR8, and TLR9 signaling pathway. | 0 |
| 38194758 | 2024 | Downregulation of transcription 1 hinders the replication of Dabie bandavirus by promoting the expression of TLR7, TLR8, and TLR9 signaling pathway. | 0 |
| 29717211 | 2018 | Up-regulation of microRNA-203 in influenza A virus infection inhibits viral replication by targeting DR1. | 26 |
| 29717211 | 2018 | Up-regulation of microRNA-203 in influenza A virus infection inhibits viral replication by targeting DR1. | 26 |
| 28181134 | 2017 | The effect and mechanism of dopamine D1 receptors on the proliferation of osteosarcoma cells. | 9 |
| 28181134 | 2017 | The effect and mechanism of dopamine D1 receptors on the proliferation of osteosarcoma cells. | 9 |
| 25589657 | 2015 | A host susceptibility gene, DR1, facilitates influenza A virus replication by suppressing host innate immunity and enhancing viral RNA replication. | 16 |
| 25589657 | 2015 | A host susceptibility gene, DR1, facilitates influenza A virus replication by suppressing host innate immunity and enhancing viral RNA replication. | 16 |
| 19965767 | 2010 | Dr1 (NC2) is present at tRNA genes and represses their transcription in human cells. | 4 |
| 20230619 | 2010 | Basal core promoters control the equilibrium between negative cofactor 2 and preinitiation complexes in human cells. | 5 |
| 20534741 | 2010 | Association of CR1, CLU and PICALM with Alzheimer's disease in a cohort of clinically characterized and neuropathologically verified individuals. | 131 |
| 19965767 | 2010 | Dr1 (NC2) is present at tRNA genes and represses their transcription in human cells. | 4 |
| 20230619 | 2010 | Basal core promoters control the equilibrium between negative cofactor 2 and preinitiation complexes in human cells. | 5 |
| 20534741 | 2010 | Association of CR1, CLU and PICALM with Alzheimer's disease in a cohort of clinically characterized and neuropathologically verified individuals. | 131 |
| 19204005 | 2009 | Regulation of nuclear import and export of negative cofactor 2. | 7 |
Citation
Dessen P
DR1 (down-regulator of transcription 1)
Atlas Genet Cytogenet Oncol Haematol. 2016-10-01
Online version: http://atlasgeneticsoncology.org/gene/56578/dr1-(down-regulator-of-transcription-1)
