MFSD12 (major facilitator superfamily domain containing 12)

2016-10-01  

Identity

HGNC
MFSD12
LOCATION
19p13.3
LOCUSID
126321
ALIAS
C19orf28,PP3501
FUSION GENES
Show Gene Fusions

Other Information

Locus ID:

NCBI: 126321
MIM: 617745
HGNC: 28299
Ensembl: ENSG00000161091

Variants:

dbSNP: 126321
ClinVar: 126321
TCGA: ENSG00000161091
COSMIC: MFSD12

RNA/Proteins

Gene IDTranscript IDUniprot
ENSG00000161091ENST00000355415Q6NUT3
ENSG00000161091ENST00000389395Q6NUT3
ENSG00000161091ENST00000398558A0A0A0MS91
ENSG00000161091ENST00000585814K7EKU1
ENSG00000161091ENST00000588626K7ERJ8
ENSG00000161091ENST00000588918Q6NUT3
ENSG00000161091ENST00000589063K7EQ22
ENSG00000161091ENST00000589995K7EJS5
ENSG00000161091ENST00000592652K7ENE1
ENSG00000161091ENST00000615073A0A087WU85
ENSG00000161091ENST00000615613Q9HBP8

Expression (GTEx)

0
5
10
15
20
25
30
35
Adipose - Subcutaneous
Adipose - Visceral
Adrenal Gland
Artery - Aorta
Artery - Tibial
Bladder
Brain - Amygdala
Brain - Anterior cingulate cortex
Brain - Caudate
Brain - Cerebellar Hemisphere
Brain - Cerebellum
Brain - Cortex
Brain - Frontal Cortex
Brain - Hippocampus
Brain - Hypothalamus
Brain - Nucleus accumbens
Brain - Putamen
Brain - Spinal cord
Brain - Substantia nigra
Breast - Mammary Tissue
Cells - Cultured fibroblasts
Cells - EBV - transformed lymphocytes
Cervix - Ectocervix
Cervix - Endocervix
Colon - Sigmoid
Colon - Transverse
Esophagus - Gastroesophageal Junction
Esophagus - Mucosa
Esophagus - Muscularis
Fallopian Tube
Heart - Atrial Appendage
Heart - Left Ventricle
Kidney - Cortex
Kidney - Medulla
Liver
Lung
Minor Salivary Gland
Muscle - Skeletal
Nerve - Tibial
Ovary
Pancreas
Pituitary
Prostate
Skin - Not Sun Exposed
Skin - Sun Exposed
Small Intestine - Terminal Ileum
Spleen
Stomach
Testis
Thyroid
Uterus
Vagina
Whole Blood

Protein levels (Protein atlas)

Not detected
Low
Medium
High
cerebral cortex
cerebellum
hippocampus
caudate
thyroid gland
parathyroid gland
adrenal gland
nasopharynx
bronchus
lung
oral mucosa
salivary gland
esophagus
stomach 1
stomach 2
duodenum
small intestine
colon
rectum
liver
gallbladder
pancreas
kidney
urinary bladder
testis
epididymis
seminal vesicle
prostate
vagina
ovary
fallopian tube
endometrium 1
endometrium 2
cervix, uterine
placenta
breast
heart muscle
smooth muscle
skeletal muscle
soft tissue 1
soft tissue 2
adipose tissue
skin 1
skin 2
appendix
spleen
lymph node
tonsil
bone marrow

References

Pubmed IDYearTitleCitations
386873512024Major Facilitator Superfamily Domain Containing 12 Is Overexpressed in Lung Cancer and Exhibits an Oncogenic Role in Lung Adenocarcinoma Cells.0
386873512024Major Facilitator Superfamily Domain Containing 12 Is Overexpressed in Lung Cancer and Exhibits an Oncogenic Role in Lung Adenocarcinoma Cells.0
332089522020MFSD12 mediates the import of cysteine into melanosomes and lysosomes.35
332089522020MFSD12 mediates the import of cysteine into melanosomes and lysosomes.35
303858542019Bioinformatics-based analysis reveals elevated MFSD12 as a key promoter of cell proliferation and a potential therapeutic target in melanoma.29
303858542019Bioinformatics-based analysis reveals elevated MFSD12 as a key promoter of cell proliferation and a potential therapeutic target in melanoma.29
224418752012Novel protein pp3501 mediates the inhibitory effect of sodium butyrate on SH-SY5Y cell proliferation.2
224418752012Novel protein pp3501 mediates the inhibitory effect of sodium butyrate on SH-SY5Y cell proliferation.2

Citation

Dessen P

MFSD12 (major facilitator superfamily domain containing 12)

Atlas Genet Cytogenet Oncol Haematol. 2016-10-01

Online version: http://atlasgeneticsoncology.org/gene/56581/mfsd12-(major-facilitator-superfamily-domain-containing-12)