PEX11A (peroxisomal biogenesis factor 11 alpha)

2016-10-01  

Identity

HGNC
LOCATION
15q26.1
LOCUSID
ALIAS
PEX11-ALPHA,PMP28,hsPEX11p

Other Information

Locus ID:

NCBI: 8800
MIM: 603866
HGNC: 8852
Ensembl: ENSG00000166821

Variants:

dbSNP: 8800
ClinVar: 8800
TCGA: ENSG00000166821
COSMIC: PEX11A

RNA/Proteins

Gene IDTranscript IDUniprot
ENSG00000166821ENST00000300056O75192
ENSG00000166821ENST00000300056B2R8C6
ENSG00000166821ENST00000559170H0YN61
ENSG00000166821ENST00000561224H0YMC7
ENSG00000166821ENST00000561257O75192

Expression (GTEx)

0
5
10
15
20

Pathways

PathwaySourceExternal ID
PeroxisomeKEGGko04146
PeroxisomeKEGGhsa04146
MetabolismREACTOMER-HSA-1430728
Metabolism of lipids and lipoproteinsREACTOMER-HSA-556833
Fatty acid, triacylglycerol, and ketone body metabolismREACTOMER-HSA-535734
Regulation of lipid metabolism by Peroxisome proliferator-activated receptor alpha (PPARalpha)REACTOMER-HSA-400206
PPARA activates gene expressionREACTOMER-HSA-1989781

References

Pubmed IDYearTitleCitations
208264552010PEX11 family members are membrane elongation factors that coordinate peroxisome proliferation and maintenance.81
208264552010PEX11 family members are membrane elongation factors that coordinate peroxisome proliferation and maintenance.81
165674222006Peroxisome proliferator-activated receptor subtypes differentially cooperate with other transcription factors in selective transactivation of the perilipin/PEX11 alpha gene pair.7
165674222006Peroxisome proliferator-activated receptor subtypes differentially cooperate with other transcription factors in selective transactivation of the perilipin/PEX11 alpha gene pair.7
124177262002PEX11alpha is required for peroxisome proliferation in response to 4-phenylbutyrate but is dispensable for peroxisome proliferator-activated receptor alpha-mediated peroxisome proliferation.53
124177262002PEX11alpha is required for peroxisome proliferation in response to 4-phenylbutyrate but is dispensable for peroxisome proliferator-activated receptor alpha-mediated peroxisome proliferation.53

Citation

Dessen P

PEX11A (peroxisomal biogenesis factor 11 alpha)

Atlas Genet Cytogenet Oncol Haematol. 2016-10-01

Online version: http://atlasgeneticsoncology.org/gene/56585/pex11a-(peroxisomal-biogenesis-factor-11-alpha)