Identity
HGNC
LOCATION
2q24.1
LOCUSID
ALIAS
ACVRLK7,ALK7
FUSION GENES
Non-annotated gene. Preliminary data : if you are an author who wish to write a full paper/card on this gene, contribute in submission tool
Other Information
Locus ID:
NCBI: 130399
MIM: 608981
HGNC: 18123
Ensembl: ENSG00000123612
Variants:
dbSNP: 130399
ClinVar: 130399
TCGA: ENSG00000123612
COSMIC: ACVR1C
RNA/Proteins
| Gene ID | Transcript ID | Uniprot |
|---|---|---|
| ENSG00000123612 | ENST00000243349 | Q8NER5 |
| ENSG00000123612 | ENST00000335450 | Q8NER5 |
| ENSG00000123612 | ENST00000348328 | Q8NER5 |
| ENSG00000123612 | ENST00000409680 | Q8NER5 |
Expression (GTEx)
Pathways
Protein levels (Protein atlas)
References
| Pubmed ID | Year | Title | Citations |
|---|---|---|---|
| 38307384 | 2024 | Human ACVR1C missense variants that correlate with altered body fat distribution produce metabolic alterations of graded severity in knock-in mutant mice. | 0 |
| 38307384 | 2024 | Human ACVR1C missense variants that correlate with altered body fat distribution produce metabolic alterations of graded severity in knock-in mutant mice. | 0 |
| 34173336 | 2022 | Regulation of metabolic homeostasis by the TGF-β superfamily receptor ALK7. | 9 |
| 35666032 | 2022 | Activin receptor-like kinase 7 silencing alleviates cardiomyocyte apoptosis, cardiac fibrosis, and dysfunction in diabetic rats. | 1 |
| 34173336 | 2022 | Regulation of metabolic homeostasis by the TGF-β superfamily receptor ALK7. | 9 |
| 35666032 | 2022 | Activin receptor-like kinase 7 silencing alleviates cardiomyocyte apoptosis, cardiac fibrosis, and dysfunction in diabetic rats. | 1 |
| 33499275 | 2021 | UV-Induced Reduction of ACVR1C Decreases SREBP1 and ACC Expression by the Suppression of SMAD2 Phosphorylation in Normal Human Epidermal Keratinocytes. | 1 |
| 33499275 | 2021 | UV-Induced Reduction of ACVR1C Decreases SREBP1 and ACC Expression by the Suppression of SMAD2 Phosphorylation in Normal Human Epidermal Keratinocytes. | 1 |
| 31608496 | 2020 | Knockdown of ALK7 inhibits high glucose-induced oxidative stress and apoptosis in retinal pigment epithelial cells. | 0 |
| 32366358 | 2020 | Control of brown adipose tissue adaptation to nutrient stress by the activin receptor ALK7. | 7 |
| 31608496 | 2020 | Knockdown of ALK7 inhibits high glucose-induced oxidative stress and apoptosis in retinal pigment epithelial cells. | 0 |
| 32366358 | 2020 | Control of brown adipose tissue adaptation to nutrient stress by the activin receptor ALK7. | 7 |
| 30367833 | 2019 | MicroRNA-454 contributes to sustaining the proliferation and invasion of trophoblast cells through inhibiting Nodal/ALK7 signaling in pre-eclampsia. | 18 |
| 30401983 | 2019 | ACVR1C/SMAD2 signaling promotes invasion and growth in retinoblastoma. | 20 |
| 31063757 | 2019 | ALK7 Signaling Manifests a Homeostatic Tissue Barrier That Is Abrogated during Tumorigenesis and Metastasis. | 20 |
Citation
Dessen P
ACVR1C (activin A receptor type 1C)
Atlas Genet Cytogenet Oncol Haematol. 2004-04-01
Online version: http://atlasgeneticsoncology.org/gene/566/acvr1c-(activin-a-receptor-type-1c)
