Non-annotated gene. Preliminary data : if you are an author who wish to write a full paper/card on this gene, contribute in submission tool
Other Information
Locus ID:
NCBI: 5024
MIM: 600843
HGNC: 8534
Ensembl: ENSG00000109991
Variants:
dbSNP: 5024
ClinVar: 5024
TCGA: ENSG00000109991
COSMIC: P2RX3
RNA/Proteins
| Gene ID | Transcript ID | Uniprot |
|---|---|---|
| ENSG00000109991 | ENST00000263314 | P56373 |
| ENSG00000109991 | ENST00000534820 | H0YDR6 |
| ENSG00000109991 | ENST00000616487 | A0A087X210 |
Expression (GTEx)
Pathways
Protein levels (Protein atlas)
References
| Pubmed ID | Year | Title | Citations |
|---|---|---|---|
| 31232692 | 2019 | Molecular mechanisms of human P2X3 receptor channel activation and modulation by divalent cation bound ATP. | 17 |
| 31232692 | 2019 | Molecular mechanisms of human P2X3 receptor channel activation and modulation by divalent cation bound ATP. | 17 |
| 29674445 | 2018 | Druggable negative allosteric site of P2X3 receptors. | 34 |
| 29674445 | 2018 | Druggable negative allosteric site of P2X3 receptors. | 34 |
| 28898282 | 2017 | P2X3 receptor involvement in endometriosis pain via ERK signaling pathway. | 21 |
| 28898282 | 2017 | P2X3 receptor involvement in endometriosis pain via ERK signaling pathway. | 21 |
| 26738991 | 2016 | Upregulated P2X3 Receptor Expression in Patients with Intractable Temporal Lobe Epilepsy and in a Rat Model of Epilepsy. | 4 |
| 26825305 | 2016 | Inter-subunit disulfide locking of the human P2X3 receptor elucidates ectodomain movements associated with channel gating. | 1 |
| 27129281 | 2016 | Modulation of P2X3 and P2X2/3 Receptors by Monoclonal Antibodies. | 11 |
| 27312548 | 2016 | Potential Involvement of P2 Receptors in the Pathological Processes of Hyperthyroidism: A Pilot Study. | 2 |
| 27626375 | 2016 | X-ray structures define human P2X(3) receptor gating cycle and antagonist action. | 120 |
| 26738991 | 2016 | Upregulated P2X3 Receptor Expression in Patients with Intractable Temporal Lobe Epilepsy and in a Rat Model of Epilepsy. | 4 |
| 26825305 | 2016 | Inter-subunit disulfide locking of the human P2X3 receptor elucidates ectodomain movements associated with channel gating. | 1 |
| 27129281 | 2016 | Modulation of P2X3 and P2X2/3 Receptors by Monoclonal Antibodies. | 11 |
| 27312548 | 2016 | Potential Involvement of P2 Receptors in the Pathological Processes of Hyperthyroidism: A Pilot Study. | 2 |
Citation
Dessen P
P2RX3 (purinergic receptor P2X 3)
Atlas Genet Cytogenet Oncol Haematol. 2016-10-01
Online version: http://atlasgeneticsoncology.org/gene/56601/p2rx3-(purinergic-receptor-p2x-3)
