DRG2 (developmentally regulated GTP binding protein 2)

2016-10-01  

Identity

HGNC
LOCATION
17p11.2
LOCUSID
ALIAS
-
FUSION GENES

Other Information

Locus ID:

NCBI: 1819
MIM: 602986
HGNC: 3030
Ensembl: ENSG00000108591

Variants:

dbSNP: 1819
ClinVar: 1819
TCGA: ENSG00000108591
COSMIC: DRG2

RNA/Proteins

Gene IDTranscript IDUniprot
ENSG00000108591ENST00000225729P55039
ENSG00000108591ENST00000395726A8MZF9
ENSG00000108591ENST00000467099J3QLF3
ENSG00000108591ENST00000496428J3QLF3
ENSG00000108591ENST00000577450J3QL90
ENSG00000108591ENST00000579224J3QRI9
ENSG00000108591ENST00000579601J3QR71
ENSG00000108591ENST00000580055J3QKW7
ENSG00000108591ENST00000580929J3KRL5
ENSG00000108591ENST00000582314J3QLF3
ENSG00000108591ENST00000582419J3QQI1
ENSG00000108591ENST00000583355J3QKV7

Expression (GTEx)

0
5
10
15
20
25
30
35
40
45

Protein levels (Protein atlas)

Not detected
Low
Medium
High

References

Pubmed IDYearTitleCitations
341904392021Developmentally regulated GTP-binding protein 2 levels in prostate cancer cell lines impact docetaxel-induced apoptosis.0
345209792021Developmentally regulated GTP-binding protein-2 regulates adipocyte differentiation.3
346640862021Developmentally regulated GTPases: structure, function and roles in disease.5
341904392021Developmentally regulated GTP-binding protein 2 levels in prostate cancer cell lines impact docetaxel-induced apoptosis.0
345209792021Developmentally regulated GTP-binding protein-2 regulates adipocyte differentiation.3
346640862021Developmentally regulated GTPases: structure, function and roles in disease.5
316932982020DRG2 supports the growth of primary tumors and metastases of melanoma by enhancing VEGF-A expression.9
316932982020DRG2 supports the growth of primary tumors and metastases of melanoma by enhancing VEGF-A expression.9
311999312019DRG2 knockdown induces Golgi fragmentation via GSK3β phosphorylation and microtubule stabilization.7
311999312019DRG2 knockdown induces Golgi fragmentation via GSK3β phosphorylation and microtubule stabilization.7
302818722018Functional intronic variant of SLC5A10 affects DRG2 expression and survival outcomes of early-stage non-small-cell lung cancer.9
304537312018DRG2 Deficiency Causes Impaired Microtubule Dynamics in HeLa Cells.5
302818722018Functional intronic variant of SLC5A10 affects DRG2 expression and survival outcomes of early-stage non-small-cell lung cancer.9
304537312018DRG2 Deficiency Causes Impaired Microtubule Dynamics in HeLa Cells.5
283638672017Developmentally regulated GTP-binding protein 2 depletion leads to mitochondrial dysfunction through downregulation of dynamin-related protein 1.5

Citation

Dessen P

DRG2 (developmentally regulated GTP binding protein 2)

Atlas Genet Cytogenet Oncol Haematol. 2016-10-01

Online version: http://atlasgeneticsoncology.org/gene/56604/tumors-explorer/gene-explorer/hgnc