Identity
HGNC
LOCATION
16q13
LOCUSID
ALIAS
CLR16.1,NOD27,NOD4
FUSION GENES
Non-annotated gene. Preliminary data : if you are an author who wish to write a full paper/card on this gene, contribute in submission tool
Other Information
Locus ID:
NCBI: 84166
MIM: 613537
HGNC: 29933
Ensembl: ENSG00000140853
Variants:
dbSNP: 84166
ClinVar: 84166
TCGA: ENSG00000140853
COSMIC: NLRC5
RNA/Proteins
Expression (GTEx)
Pathways
References
| Pubmed ID | Year | Title | Citations |
|---|---|---|---|
| 38231444 | 2024 | Rescue of NLRC5 expression restores antigen processing machinery in head and neck cancer cells lacking functional STAT1 and p53. | 0 |
| 38519032 | 2024 | The balance between nuclear import and export of NLRC5 regulates MHC class I transactivation. | 1 |
| 38961101 | 2024 | NLRC5 promotes tumorigenesis by regulating the PI3K/AKT signaling pathway in cervical cancer. | 0 |
| 38231444 | 2024 | Rescue of NLRC5 expression restores antigen processing machinery in head and neck cancer cells lacking functional STAT1 and p53. | 0 |
| 38519032 | 2024 | The balance between nuclear import and export of NLRC5 regulates MHC class I transactivation. | 1 |
| 38961101 | 2024 | NLRC5 promotes tumorigenesis by regulating the PI3K/AKT signaling pathway in cervical cancer. | 0 |
| 36126167 | 2023 | NLRC5 restricts dengue virus infection by promoting the autophagic degradation of viral NS3 through E3 ligase CUL2 (cullin 2). | 8 |
| 36372300 | 2023 | USP14-mediated NLRC5 upregulation inhibits endothelial cell activation and inflammation in atherosclerosis. | 4 |
| 37108368 | 2023 | NLRC5-CIITA Fusion Protein as an Effective Inducer of MHC-I Expression and Antitumor Immunity. | 2 |
| 37277194 | 2023 | NLRC5 germline variants as potential pharmacogenomic markers for immune checkpoint inhibitors. | 0 |
| 38235131 | 2023 | NLRC5 overexpression in ovarian tumors remodels the tumor microenvironment and increases T-cell reactivity toward autologous tumor-associated antigens. | 1 |
| 36126167 | 2023 | NLRC5 restricts dengue virus infection by promoting the autophagic degradation of viral NS3 through E3 ligase CUL2 (cullin 2). | 8 |
| 36372300 | 2023 | USP14-mediated NLRC5 upregulation inhibits endothelial cell activation and inflammation in atherosclerosis. | 4 |
| 37108368 | 2023 | NLRC5-CIITA Fusion Protein as an Effective Inducer of MHC-I Expression and Antitumor Immunity. | 2 |
| 37277194 | 2023 | NLRC5 germline variants as potential pharmacogenomic markers for immune checkpoint inhibitors. | 0 |
Citation
Dessen P
NLRC5 (NLR family CARD domain containing 5)
Atlas Genet Cytogenet Oncol Haematol. 2016-10-01
Online version: http://atlasgeneticsoncology.org/gene/56616/nlrc5-(nlr-family-card-domain-containing-5)
