MAGT1 (magnesium transporter 1)

2016-10-01  

Identity

HGNC
LOCATION
Xq21.1
LOCUSID
ALIAS
CDG1CC,IAP,MRX95,OST3B,PRO0756,SLC58A1,XMEN,bA217H1.1
FUSION GENES

Other Information

Locus ID:

NCBI: 84061
MIM: 300715
HGNC: 28880
Ensembl: ENSG00000102158

Variants:

dbSNP: 84061
ClinVar: 84061
TCGA: ENSG00000102158
COSMIC: MAGT1

RNA/Proteins

Gene IDTranscript IDUniprot
ENSG00000102158ENST00000358075A0A087WU53
ENSG00000102158ENST00000373336Q9H0U3
ENSG00000102158ENST00000610432A0A087WU53
ENSG00000102158ENST00000618282Q9H0U3

Expression (GTEx)

0
10
20
30
40
50
60

Pathways

PathwaySourceExternal ID
Metabolism of proteinsREACTOMER-HSA-392499
Post-translational protein modificationREACTOMER-HSA-597592
Asparagine N-linked glycosylationREACTOMER-HSA-446203
Immune SystemREACTOMER-HSA-168256
Innate Immune SystemREACTOMER-HSA-168249
Transmembrane transport of small moleculesREACTOMER-HSA-382551
Miscellaneous transport and binding eventsREACTOMER-HSA-5223345
Neutrophil degranulationREACTOMER-HSA-6798695

Protein levels (Protein atlas)

Not detected
Low
Medium
High

References

Pubmed IDYearTitleCitations
388961222024HLH and Recurrent EBV Lymphoma as the presenting manifestation of MAGT1 Deficiency: A Systematic Review of the Expanding Disease Spectrum.0
388961222024HLH and Recurrent EBV Lymphoma as the presenting manifestation of MAGT1 Deficiency: A Systematic Review of the Expanding Disease Spectrum.0
352647852022Identification of a novel MAGT1 mutation supports a diagnosis of XMEN disease.4
354307132022Long non-coding RNA FLVCR1-AS1 functions as a ceRNA to aggravate cervical cancer cell growth by the miR-381-3p/MAGT1 axis.3
357960072022Transcription factor KLF16 activates MAGT1 to regulate the tumorigenesis and progression of breast cancer.2
352647852022Identification of a novel MAGT1 mutation supports a diagnosis of XMEN disease.4
354307132022Long non-coding RNA FLVCR1-AS1 functions as a ceRNA to aggravate cervical cancer cell growth by the miR-381-3p/MAGT1 axis.3
357960072022Transcription factor KLF16 activates MAGT1 to regulate the tumorigenesis and progression of breast cancer.2
340868702021CRISPR-targeted MAGT1 insertion restores XMEN patient hematopoietic stem cells and lymphocytes.10
344995812021MAGT1 is required for HeLa cell proliferation through regulating p21 expression, S-phase progress, and ERK/p38 MAPK MYC axis.5
340868702021CRISPR-targeted MAGT1 insertion restores XMEN patient hematopoietic stem cells and lymphocytes.10
344995812021MAGT1 is required for HeLa cell proliferation through regulating p21 expression, S-phase progress, and ERK/p38 MAPK MYC axis.5
326337232020TRPM7 and MagT1 regulate the proliferation of osteoblast-like SaOS-2 cells through different mechanisms.1
332106052020miR-199a-5p targeted regulation of MAGT1 expression in the functional depletion of CD8(+)T cells in HBV infection.0
326337232020TRPM7 and MagT1 regulate the proliferation of osteoblast-like SaOS-2 cells through different mechanisms.1

Citation

Dessen P

MAGT1 (magnesium transporter 1)

Atlas Genet Cytogenet Oncol Haematol. 2016-10-01

Online version: http://atlasgeneticsoncology.org/gene/56622/magt1-(magnesium-transporter-1)