Identity
HGNC
LOCATION
12q21.31
LOCUSID
ALIAS
LIN-7A,LIN7,MALS-1,MALS1,TIP-33,VELI1
FUSION GENES
Non-annotated gene. Preliminary data : if you are an author who wish to write a full paper/card on this gene, contribute in submission tool
Other Information
Locus ID:
NCBI: 8825
MIM: 603380
HGNC: 17787
Ensembl: ENSG00000111052
Variants:
dbSNP: 8825
ClinVar: 8825
TCGA: ENSG00000111052
COSMIC: LIN7A
RNA/Proteins
| Gene ID | Transcript ID | Uniprot |
|---|---|---|
| ENSG00000111052 | ENST00000261203 | J3KN23 |
| ENSG00000111052 | ENST00000549417 | H0YIA8 |
| ENSG00000111052 | ENST00000552093 | H0YI92 |
| ENSG00000111052 | ENST00000552864 | O14910 |
Expression (GTEx)
Pathways
Protein levels (Protein atlas)
References
| Pubmed ID | Year | Title | Citations |
|---|---|---|---|
| 29749382 | 2018 | microRNA-501-3p suppresses metastasis and progression of hepatocellular carcinoma through targeting LIN7A. | 20 |
| 29749382 | 2018 | microRNA-501-3p suppresses metastasis and progression of hepatocellular carcinoma through targeting LIN7A. | 20 |
| 26887652 | 2016 | LIN7A is a major determinant of cell-polarity defects in breast carcinomas. | 10 |
| 27320196 | 2016 | Novel localisation and possible function of LIN7 and IRSp53 in mitochondria of HeLa cells. | 4 |
| 26887652 | 2016 | LIN7A is a major determinant of cell-polarity defects in breast carcinomas. | 10 |
| 27320196 | 2016 | Novel localisation and possible function of LIN7 and IRSp53 in mitochondria of HeLa cells. | 4 |
| 24658322 | 2014 | LIN7A depletion disrupts cerebral cortex development, contributing to intellectual disability in 12q21-deletion syndrome. | 10 |
| 24658322 | 2014 | LIN7A depletion disrupts cerebral cortex development, contributing to intellectual disability in 12q21-deletion syndrome. | 10 |
| 20379614 | 2010 | Personalized smoking cessation: interactions between nicotine dose, dependence and quit-success genotype score. | 78 |
| 20379614 | 2010 | Personalized smoking cessation: interactions between nicotine dose, dependence and quit-success genotype score. | 78 |
| 18286632 | 2008 | Association study of brain-derived neurotrophic factor (BDNF) and LIN-7 homolog (LIN-7) genes with adult attention-deficit/hyperactivity disorder. | 16 |
| 18286632 | 2008 | Association study of brain-derived neurotrophic factor (BDNF) and LIN-7 homolog (LIN-7) genes with adult attention-deficit/hyperactivity disorder. | 16 |
| 17237226 | 2007 | The stardust family protein MPP7 forms a tripartite complex with LIN7 and DLG1 that regulates the stability and localization of DLG1 to cell junctions. | 37 |
| 17237226 | 2007 | The stardust family protein MPP7 forms a tripartite complex with LIN7 and DLG1 that regulates the stability and localization of DLG1 to cell junctions. | 37 |
| 12110687 | 2002 | Coordinated folding and association of the LIN-2, -7 (L27) domain. An obligate heterodimerization involved in assembly of signaling and cell polarity complexes. | 10 |
Citation
Dessen P
LIN7A (lin-7 homolog A, crumbs cell polarity complex component)
Atlas Genet Cytogenet Oncol Haematol. 2016-10-01
Online version: http://atlasgeneticsoncology.org/gene/56624/lin7a-(lin-7-homolog-a-crumbs-cell-polarity-complex-component)
