SLC2A14 (solute carrier family 2 member 14)

2016-10-01  

Identity

HGNC
SLC2A14
LOCATION
12p13.31
LOCUSID
144195
ALIAS
GLUT14,SLC2A3P3
FUSION GENES
Show Gene Fusions

Other Information

Locus ID:

NCBI: 144195
MIM: 611039
HGNC: 18301
Ensembl: ENSG00000173262

Variants:

dbSNP: 144195
ClinVar: 144195
TCGA: ENSG00000173262
COSMIC: SLC2A14

RNA/Proteins

Gene IDTranscript IDUniprot
ENSG00000173262ENST00000340749Q8TDB8
ENSG00000173262ENST00000396589Q8TDB8
ENSG00000173262ENST00000431042Q8TDB8
ENSG00000173262ENST00000535266F5H6F6
ENSG00000173262ENST00000535295Q8TDB8
ENSG00000173262ENST00000535344F5H5Q3
ENSG00000173262ENST00000535383F5H5V7
ENSG00000173262ENST00000535587F5H3J0
ENSG00000173262ENST00000536594F5GXT4
ENSG00000173262ENST00000537557F5GXP7
ENSG00000173262ENST00000539234F5H565
ENSG00000173262ENST00000539924Q8TDB8
ENSG00000173262ENST00000542505Q8TDB8
ENSG00000173262ENST00000542546Q8TDB8
ENSG00000173262ENST00000542782F5H076
ENSG00000173262ENST00000542916F5H7N2
ENSG00000173262ENST00000543909Q8TDB8
ENSG00000173262ENST00000546234F5GXP8
ENSG00000173262ENST00000616981Q8TDB8

Expression (GTEx)

0
10
20
30
40
50
60
70
Adipose - Subcutaneous
Adipose - Visceral
Adrenal Gland
Artery - Aorta
Artery - Tibial
Bladder
Brain - Amygdala
Brain - Anterior cingulate cortex
Brain - Caudate
Brain - Cerebellar Hemisphere
Brain - Cerebellum
Brain - Cortex
Brain - Frontal Cortex
Brain - Hippocampus
Brain - Hypothalamus
Brain - Nucleus accumbens
Brain - Putamen
Brain - Spinal cord
Brain - Substantia nigra
Breast - Mammary Tissue
Cells - Cultured fibroblasts
Cells - EBV - transformed lymphocytes
Cervix - Ectocervix
Cervix - Endocervix
Colon - Sigmoid
Colon - Transverse
Esophagus - Gastroesophageal Junction
Esophagus - Mucosa
Esophagus - Muscularis
Fallopian Tube
Heart - Atrial Appendage
Heart - Left Ventricle
Kidney - Cortex
Kidney - Medulla
Liver
Lung
Minor Salivary Gland
Muscle - Skeletal
Nerve - Tibial
Ovary
Pancreas
Pituitary
Prostate
Skin - Not Sun Exposed
Skin - Sun Exposed
Small Intestine - Terminal Ileum
Spleen
Stomach
Testis
Thyroid
Uterus
Vagina
Whole Blood

Pathways

PathwaySourceExternal ID
Transmembrane transport of small moleculesREACTOMER-HSA-382551
SLC-mediated transmembrane transportREACTOMER-HSA-425407
Hexose transportREACTOMER-HSA-189200
Glucose transportREACTOMER-HSA-70153
Transport of glucose and other sugars, bile salts and organic acids, metal ions and amine compoundsREACTOMER-HSA-425366
Facilitative Na+-independent glucose transportersREACTOMER-HSA-428790
MetabolismREACTOMER-HSA-1430728
Metabolism of carbohydratesREACTOMER-HSA-71387

Protein levels (Protein atlas)

Not detected
Low
Medium
High
cerebral cortex
cerebellum
hippocampus
caudate
thyroid gland
parathyroid gland
nasopharynx
bronchus
lung
oral mucosa
salivary gland
esophagus
stomach 1
stomach 2
duodenum
small intestine
colon
rectum
liver
gallbladder
pancreas
kidney
urinary bladder
testis
epididymis
seminal vesicle
prostate
vagina
ovary
fallopian tube
endometrium 1
endometrium 2
cervix, uterine
placenta
breast
heart muscle
smooth muscle
skeletal muscle
soft tissue 1
soft tissue 2
adipose tissue
skin 1
skin 2
appendix
spleen
lymph node
tonsil
bone marrow

References

Pubmed IDYearTitleCitations
308859922019Adaptation to HIF1α Deletion in Hypoxic Cancer Cells by Upregulation of GLUT14 and Creatine Metabolism.13
308859922019Adaptation to HIF1α Deletion in Hypoxic Cancer Cells by Upregulation of GLUT14 and Creatine Metabolism.13
289718502017The SLC2A14 gene, encoding the novel glucose/dehydroascorbate transporter GLUT14, is associated with inflammatory bowel disease.16
289718502017The SLC2A14 gene, encoding the novel glucose/dehydroascorbate transporter GLUT14, is associated with inflammatory bowel disease.16
274608882016The SLC2A14 gene: genomic locus, tissue expression, splice variants, and subcellular localization of the protein.9
274608882016The SLC2A14 gene: genomic locus, tissue expression, splice variants, and subcellular localization of the protein.9
261838392015Both GLUT-1 and GLUT-14 are Independent Prognostic Factors in Gastric Adenocarcinoma.25
261838392015Both GLUT-1 and GLUT-14 are Independent Prognostic Factors in Gastric Adenocarcinoma.25
224218042012Genetic association of SLC2A14 polymorphism with Alzheimer's disease in a Han Chinese population.9
224218042012Genetic association of SLC2A14 polymorphism with Alzheimer's disease in a Han Chinese population.9

Citation

Dessen P

SLC2A14 (solute carrier family 2 member 14)

Atlas Genet Cytogenet Oncol Haematol. 2016-10-01

Online version: http://atlasgeneticsoncology.org/gene/56625/slc2a14-(solute-carrier-family-2-member-14)