Identity
HGNC
LOCATION
14q24.3
LOCUSID
ALIAS
P24(DELTA),S31I125,S31III125,TMP21,Tmp-21-I,p23,p24d1
FUSION GENES
Non-annotated gene. Preliminary data : if you are an author who wish to write a full paper/card on this gene, contribute in submission tool
Other Information
Locus ID:
NCBI: 10972
MIM: 605406
HGNC: 16998
Ensembl: ENSG00000170348
Variants:
dbSNP: 10972
ClinVar: 10972
TCGA: ENSG00000170348
COSMIC: TMED10
RNA/Proteins
| Gene ID | Transcript ID | Uniprot |
|---|---|---|
| ENSG00000170348 | ENST00000303575 | P49755 |
| ENSG00000170348 | ENST00000303575 | A0A024R6I3 |
| ENSG00000170348 | ENST00000555873 | G3V2K7 |
Expression (GTEx)
Pathways
Protein levels (Protein atlas)
References
| Pubmed ID | Year | Title | Citations |
|---|---|---|---|
| 32293333 | 2020 | The circular RNA CDR1as regulate cell proliferation via TMED2 and TMED10. | 8 |
| 32293333 | 2020 | The circular RNA CDR1as regulate cell proliferation via TMED2 and TMED10. | 8 |
| 30821607 | 2019 | Down-regulated TMED10 in Alzheimer disease induces autophagy via ATG4B activation. | 16 |
| 30996093 | 2019 | A Genome-Wide Haploid Genetic Screen Identifies Heparan Sulfate-Associated Genes and the Macropinocytosis Modulator TMED10 as Factors Supporting Vaccinia Virus Infection. | 21 |
| 31472964 | 2019 | TMP21 regulates autophagy by modulating ROS production and mTOR activation. | 3 |
| 30821607 | 2019 | Down-regulated TMED10 in Alzheimer disease induces autophagy via ATG4B activation. | 16 |
| 30996093 | 2019 | A Genome-Wide Haploid Genetic Screen Identifies Heparan Sulfate-Associated Genes and the Macropinocytosis Modulator TMED10 as Factors Supporting Vaccinia Virus Infection. | 21 |
| 31472964 | 2019 | TMP21 regulates autophagy by modulating ROS production and mTOR activation. | 3 |
| 28233271 | 2018 | A Novel Alzheimer-Associated SNP in Tmp21 Increases Amyloidogenesis. | 9 |
| 28233271 | 2018 | A Novel Alzheimer-Associated SNP in Tmp21 Increases Amyloidogenesis. | 9 |
| 28115518 | 2017 | TMED10 Protein Interferes with Transforming Growth Factor (TGF)-β Signaling by Disrupting TGF-β Receptor Complex Formation. | 11 |
| 28115518 | 2017 | TMED10 Protein Interferes with Transforming Growth Factor (TGF)-β Signaling by Disrupting TGF-β Receptor Complex Formation. | 11 |
| 27569046 | 2016 | 3D Structure and Interaction of p24β and p24δ Golgi Dynamics Domains: Implication for p24 Complex Formation and Cargo Transport. | 20 |
| 27569046 | 2016 | 3D Structure and Interaction of p24β and p24δ Golgi Dynamics Domains: Implication for p24 Complex Formation and Cargo Transport. | 20 |
| 26617795 | 2015 | TMP21 modulates cell growth in papillary thyroid cancer cells by inducing autophagy through activation of the AMPK/mTOR pathway. | 13 |
Citation
Dessen P
TMED10 (transmembrane p24 trafficking protein 10)
Atlas Genet Cytogenet Oncol Haematol. 2016-10-01
Online version: http://atlasgeneticsoncology.org/gene/56626/tmed10-(transmembrane-p24-trafficking-protein-10)
