Non-annotated gene. Preliminary data : if you are an author who wish to write a full paper/card on this gene, contribute in submission tool
Other Information
Locus ID:
NCBI: 9696
MIM: 615776
HGNC: 21299
Ensembl: ENSG00000058453
Variants:
dbSNP: 9696
ClinVar: 9696
TCGA: ENSG00000058453
COSMIC: CROCC
RNA/Proteins
| Gene ID | Transcript ID | Uniprot |
|---|---|---|
| ENSG00000058453 | ENST00000375541 | Q5TZA2 |
| ENSG00000058453 | ENST00000445545 | B1AKD8 |
| ENSG00000058453 | ENST00000467715 | A0A087WU09 |
| ENSG00000058453 | ENST00000467938 | A0A087WW81 |
Expression (GTEx)
Protein levels (Protein atlas)
References
| Pubmed ID | Year | Title | Citations |
|---|---|---|---|
| 31799620 | 2020 | Up-regulated microRNA-33b inhibits epithelial-mesenchymal transition in gallbladder cancer through down-regulating CROCC. | 5 |
| 32325071 | 2020 | Identification of a Structurally Dynamic Domain for Oligomer Formation in Rootletin. | 7 |
| 31799620 | 2020 | Up-regulated microRNA-33b inhibits epithelial-mesenchymal transition in gallbladder cancer through down-regulating CROCC. | 5 |
| 32325071 | 2020 | Identification of a Structurally Dynamic Domain for Oligomer Formation in Rootletin. | 7 |
| 29463719 | 2018 | STED nanoscopy of the centrosome linker reveals a CEP68-organized, periodic rootletin network anchored to a C-Nap1 ring at centrioles. | 35 |
| 29649211 | 2018 | Stable centrosomal roots disentangle to allow interphase centriole independence. | 8 |
| 29463719 | 2018 | STED nanoscopy of the centrosome linker reveals a CEP68-organized, periodic rootletin network anchored to a C-Nap1 ring at centrioles. | 35 |
| 29649211 | 2018 | Stable centrosomal roots disentangle to allow interphase centriole independence. | 8 |
| 28089774 | 2017 | Rootletin prevents Cep68 from VHL-mediated proteasomal degradation to maintain centrosome cohesion. | 9 |
| 28089774 | 2017 | Rootletin prevents Cep68 from VHL-mediated proteasomal degradation to maintain centrosome cohesion. | 9 |
| 24240686 | 2014 | The tumor suppressor, TAX1BP2, is a novel substrate of ATM kinase. | 1 |
| 24240686 | 2014 | The tumor suppressor, TAX1BP2, is a novel substrate of ATM kinase. | 1 |
| 22610972 | 2012 | The centrosomal protein Tax1 binding protein 2 is a novel tumor suppressor in hepatocellular carcinoma regulated by cyclin-dependent kinase 2. | 5 |
| 23070519 | 2012 | C-NAP1 and rootletin restrain DNA damage-induced centriole splitting and facilitate ciliogenesis. | 23 |
| 22610972 | 2012 | The centrosomal protein Tax1 binding protein 2 is a novel tumor suppressor in hepatocellular carcinoma regulated by cyclin-dependent kinase 2. | 5 |
Citation
Dessen P
CROCC (ciliary rootlet coiled-coil, rootletin)
Atlas Genet Cytogenet Oncol Haematol. 2016-10-01
Online version: http://atlasgeneticsoncology.org/gene/56628/tumors-explorer/
