Identity
HGNC
LOCATION
9q21.31
LOCUSID
ALIAS
BCE-1,BCE1,E(spI),E(spl),ESG,ESG4,GRG4,Grg-4
FUSION GENES
Non-annotated gene. Preliminary data : if you are an author who wish to write a full paper/card on this gene, contribute in submission tool
Other Information
Locus ID:
NCBI: 7091
MIM: 605132
HGNC: 11840
Ensembl: ENSG00000106829
Variants:
dbSNP: 7091
ClinVar: 7091
TCGA: ENSG00000106829
COSMIC: TLE4
RNA/Proteins
Expression (GTEx)
Pathways
References
| Pubmed ID | Year | Title | Citations |
|---|---|---|---|
| 35099008 | 2022 | TLE4 regulates muscle stem cell quiescence and skeletal muscle differentiation. | 9 |
| 35099008 | 2022 | TLE4 regulates muscle stem cell quiescence and skeletal muscle differentiation. | 9 |
| 28262390 | 2017 | Polymorphisms of TGFB1, TLE4 and MUC22 are associated with childhood asthma in Chinese population. | 8 |
| 28262390 | 2017 | Polymorphisms of TGFB1, TLE4 and MUC22 are associated with childhood asthma in Chinese population. | 8 |
| 26701208 | 2016 | TLE4 promotes colorectal cancer progression through activation of JNK/c-Jun signaling pathway. | 27 |
| 27486062 | 2016 | TLE4 regulation of wnt-mediated inflammation underlies its role as a tumor suppressor in myeloid leukemia. | 10 |
| 26701208 | 2016 | TLE4 promotes colorectal cancer progression through activation of JNK/c-Jun signaling pathway. | 27 |
| 27486062 | 2016 | TLE4 regulation of wnt-mediated inflammation underlies its role as a tumor suppressor in myeloid leukemia. | 10 |
| 25631048 | 2015 | The Groucho-associated phosphatase PPM1B displaces Pax transactivation domain interacting protein (PTIP) to switch the transcription factor Pax2 from a transcriptional activator to a repressor. | 15 |
| 25631048 | 2015 | The Groucho-associated phosphatase PPM1B displaces Pax transactivation domain interacting protein (PTIP) to switch the transcription factor Pax2 from a transcriptional activator to a repressor. | 15 |
| 24099773 | 2013 | The Groucho protein Grg4 suppresses Smad7 to activate BMP signaling. | 7 |
| 24099773 | 2013 | The Groucho protein Grg4 suppresses Smad7 to activate BMP signaling. | 7 |
| 22169276 | 2012 | Epigenetic mechanisms of Groucho/Grg/TLE mediated transcriptional repression. | 41 |
| 22927467 | 2012 | SUMOylated SoxE factors recruit Grg4 and function as transcriptional repressors in the neural crest. | 33 |
| 22169276 | 2012 | Epigenetic mechanisms of Groucho/Grg/TLE mediated transcriptional repression. | 41 |
Citation
Dessen P
TLE4 (TLE family member 4, transcriptional corepressor)
Atlas Genet Cytogenet Oncol Haematol. 2016-12-01
Online version: http://atlasgeneticsoncology.org/gene/56639/tle4-(tle-family-member-4-transcriptional-corepressor)
