Identity
HGNC
LOCATION
10q22.1
LOCUSID
ALIAS
B7-H5,B7H5,C10orf54,DD1alpha,Dies1,GI24,PD-1H,PP2135,SISP1,VISTA
Non-annotated gene. Preliminary data : if you are an author who wish to write a full paper/card on this gene, contribute in submission tool
Other Information
Locus ID:
NCBI: 64115
MIM: 615608
HGNC: 30085
Ensembl: ENSG00000107738
Variants:
dbSNP: 64115
ClinVar: 64115
TCGA: ENSG00000107738
COSMIC: VSIR
RNA/Proteins
| Gene ID | Transcript ID | Uniprot |
|---|---|---|
| ENSG00000107738 | ENST00000394957 | Q9H7M9 |
Expression (GTEx)
References
| Pubmed ID | Year | Title | Citations |
|---|---|---|---|
| 37562584 | 2024 | Immune Inhibitory Molecule PD-1 Homolog (VISTA) Colocalizes with CD11b Myeloid Cells in Melanoma and Is Associated with Poor Outcomes. | 0 |
| 38042220 | 2024 | Dual silencing of tumor-intrinsic VISTA and CTLA-4 stimulates T-cell mediated immune responses and inhibits MCF7 breast cancer development. | 1 |
| 38060328 | 2024 | PD-1H/VISTA mediates immune evasion in acute myeloid leukemia. | 0 |
| 38175754 | 2024 | VISTA promotes the metabolism and differentiation of myeloid-derived suppressor cells by STAT3 and polyamine-dependent mechanisms. | 2 |
| 38357542 | 2024 | Unraveling the potential of CD8, CD68, and VISTA as diagnostic and prognostic markers in patients with pancreatic ductal adenocarcinoma. | 3 |
| 38850312 | 2024 | Aberrant expression of B7-H4 and B7-H5 contributes to the development of cutaneous squamous cell carcinoma. | 0 |
| 37562584 | 2024 | Immune Inhibitory Molecule PD-1 Homolog (VISTA) Colocalizes with CD11b Myeloid Cells in Melanoma and Is Associated with Poor Outcomes. | 0 |
| 38042220 | 2024 | Dual silencing of tumor-intrinsic VISTA and CTLA-4 stimulates T-cell mediated immune responses and inhibits MCF7 breast cancer development. | 1 |
| 38060328 | 2024 | PD-1H/VISTA mediates immune evasion in acute myeloid leukemia. | 0 |
| 38175754 | 2024 | VISTA promotes the metabolism and differentiation of myeloid-derived suppressor cells by STAT3 and polyamine-dependent mechanisms. | 2 |
| 38357542 | 2024 | Unraveling the potential of CD8, CD68, and VISTA as diagnostic and prognostic markers in patients with pancreatic ductal adenocarcinoma. | 3 |
| 38850312 | 2024 | Aberrant expression of B7-H4 and B7-H5 contributes to the development of cutaneous squamous cell carcinoma. | 0 |
| 36042047 | 2023 | Immune checkpoint receptor VISTA on immune cells is associated with expression of T-cell exhaustion marker TOX and worse prognosis in renal cell carcinoma with venous tumor thrombus. | 6 |
| 36450109 | 2023 | VISTA (PD-1H) Is a Crucial Immune Regulator to Limit Pulmonary Fibrosis. | 3 |
| 36849939 | 2023 | Targeting STAT3-VISTA axis to suppress tumor aggression and burden in acute myeloid leukemia. | 6 |
Citation
Dessen P
VSIR (V-set immunoregulatory receptor)
Atlas Genet Cytogenet Oncol Haematol. 2016-12-01
Online version: http://atlasgeneticsoncology.org/gene/56664/
