Non-annotated gene. Preliminary data : if you are an author who wish to write a full paper/card on this gene, contribute in submission tool
Other Information
Locus ID:
NCBI: 6921
MIM: 600788
HGNC: 11617
Ensembl: ENSG00000154582
Variants:
dbSNP: 6921
ClinVar: 6921
TCGA: ENSG00000154582
COSMIC: ELOC
RNA/Proteins
Expression (GTEx)
Pathways
References
| Pubmed ID | Year | Title | Citations |
|---|---|---|---|
| 38058035 | 2023 | [Clinicopathological and molecular genetic characteristics of ELOC mutated renal cell carcinoma]. | 0 |
| 38058035 | 2023 | [Clinicopathological and molecular genetic characteristics of ELOC mutated renal cell carcinoma]. | 0 |
| 31813809 | 2021 | Putative Drivers of Aggressiveness in TCEB1-mutant Renal Cell Carcinoma: An Emerging Entity with Variable Clinical Course. | 11 |
| 34163032 | 2021 | NF-κB-activated SPRY4-IT1 promotes cancer cell metastasis by downregulating TCEB1 mRNA via Staufen1-mediated mRNA decay. | 12 |
| 31813809 | 2021 | Putative Drivers of Aggressiveness in TCEB1-mutant Renal Cell Carcinoma: An Emerging Entity with Variable Clinical Course. | 11 |
| 34163032 | 2021 | NF-κB-activated SPRY4-IT1 promotes cancer cell metastasis by downregulating TCEB1 mRNA via Staufen1-mediated mRNA decay. | 12 |
| 31850909 | 2020 | "Renal Cell Carcinoma With Leiomyomatous Stroma" Harbor Somatic Mutations of TSC1, TSC2, MTOR, and/or ELOC (TCEB1): Clinicopathologic and Molecular Characterization of 18 Sporadic Tumors Supports a Distinct Entity. | 17 |
| 31941775 | 2020 | Elongin C Contributes to RNA Polymerase II Degradation by the Interferon Antagonist NSs of La Crosse Orthobunyavirus. | 6 |
| 32303605 | 2020 | Novel genetic characterisation and phenotype correlation in von Hippel-Lindau (VHL) disease based on the Elongin C binding site: a large retrospective study. | 2 |
| 31850909 | 2020 | "Renal Cell Carcinoma With Leiomyomatous Stroma" Harbor Somatic Mutations of TSC1, TSC2, MTOR, and/or ELOC (TCEB1): Clinicopathologic and Molecular Characterization of 18 Sporadic Tumors Supports a Distinct Entity. | 17 |
| 31941775 | 2020 | Elongin C Contributes to RNA Polymerase II Degradation by the Interferon Antagonist NSs of La Crosse Orthobunyavirus. | 6 |
| 32303605 | 2020 | Novel genetic characterisation and phenotype correlation in von Hippel-Lindau (VHL) disease based on the Elongin C binding site: a large retrospective study. | 2 |
| 30166453 | 2018 | CRL4(AMBRA1) targets Elongin C for ubiquitination and degradation to modulate CRL5 signaling. | 12 |
| 30166453 | 2018 | CRL4(AMBRA1) targets Elongin C for ubiquitination and degradation to modulate CRL5 signaling. | 12 |
| 25661653 | 2015 | Insights into Cullin-RING E3 ubiquitin ligase recruitment: structure of the VHL-EloBC-Cul2 complex. | 41 |
Citation
Dessen P
ELOC (elongin C)
Atlas Genet Cytogenet Oncol Haematol. 2016-12-01
Online version: http://atlasgeneticsoncology.org/gene/56669
